1332/10 | Tocris Bioscience 1332/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

1332/10

catalog :

1332/10

quantity :

10 mg (also 50 mg)

price :

251 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Agasse F, Mendez David I, Christaller W, Carpentier R, Braz B, David D, et al. Chronic Corticosterone Elevation Suppresses Adult Hippocampal Neurogenesis by Hyperphosphorylating Huntingtin. Cell Rep. 2020;32:107865 pubmed publisher

product information

master code :

1332

SKU :

1332/10

product name :

Roscovitine

unit size :

10 mg (also 50 mg)

description :

Cdk inhibitor

target :

Cyclin-dependent Kinase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

354.45

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Roscovitine is a cyclin-dependent kinase (cdk) inhibitor. Displays sub-micromolar inhibition of cdk1, cdk2, cdk5, cdk7 and cdk9 (reported IC50 values range from 0.16 - 0.28 M for cdk5 to 0.8 M for cdk7). Selective for cdks over a wide range of related kinases including ERK1 and ERK2. Arrests L1210 cells in G1 phase. Inhibits phosphorylation of vimentin in vivo . Antimitotic.

top caption :

Cdk inhibitor

extended description :

Cdk inhibitor

chemical name text :

(2R)-2-[[9-(1-Methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-butanol

formula :

C19H26N6O

cas num :

186692-46-6

USD :

251 USD

product details :

Cdk inhibitor

alt names :

CYC 202,Seliciclib

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage