Flumazenil | Tocris Bioscience 1328 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Flumazenil

catalog :

1328

quantity :

10 mg (also 50 mg)

price :

102 USD

more info or order :

Tocris Bioscience product webpage

citations: 7

Reference
Brodnik Z, Batra A, Oleson E, Espana R. Local GABAA Receptor-Mediated Suppression of Dopamine Release within the Nucleus Accumbens. ACS Chem Neurosci. 2019;10:1978-1985 pubmed publisher
Maya Mendoza A, Moudry P, Merchut Maya J, Lee M, Strauss R, Bartek J. High speed of fork progression induces DNA replication stress and genomic instability. Nature. 2018;559:279-284 pubmed publisher
Joensuu T, Tegelberg S, Reinmaa E, Segerstrale M, Hakala P, Pehkonen H, et al. Gene expression alterations in the cerebellum and granule neurons of Cstb(-/-) mouse are associated with early synaptic changes and inflammation. PLoS ONE. 2014;9:e89321 pubmed publisher
Heidelberg L, Warren J, Fisher J. SB-205384 is a positive allosteric modulator of recombinant GABAA receptors containing rat ?3, ?5, or ?6 subunit subtypes coexpressed with ?3 and ?2 subunits. J Pharmacol Exp Ther. 2013;347:235-41 pubmed publisher
Carlile E, Shirachi D, Quock R. An anxiolytic-like effect of hyperbaric oxygen in the mouse light/dark exploration test. Life Sci. 2012;90:267-71 pubmed publisher
Leppä E, Linden A, Vekovischeva O, Swinny J, Rantanen V, Toppila E, et al. Removal of GABA(A) receptor ?2 subunits from parvalbumin neurons causes wide-ranging behavioral alterations. PLoS ONE. 2011;6:e24159 pubmed publisher
Linden A, Schmitt U, Leppä E, Wulff P, Wisden W, Lüddens H, et al. Ro 15-4513 Antagonizes Alcohol-Induced Sedation in Mice Through ???2-type GABA(A) Receptors. Front Neurosci. 2011;5:3 pubmed publisher

product information

brand :

Tocris

master code :

1328

SKU :

1328/10

product name :

Flumazenil

description :

Benzodiazepine antagonist

target :

GABA-A Receptor Benzodiazepines

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

303.29

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Benzodiazepine antagonist, non-selective for 1, 2, 3 or 5-containing GABAA receptors. Centrally active upon systemic administration in vivo . Also inhibits repressor element-1 silencing transcription factor (REST) by targeting degradation.

catalog number base :

1328

product keywords :

Benzodiazepine antagonists GABAA Receptors Ro151788 repressor element-1 silencing transcription factor REST inhibitors inhibits Ro 15-1788 GABAA Receptors Other Transcription Factors 1328,

extended description :

Benzodiazepine antagonist

chemical name text :

8-Fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, ethyl ester

formula :

C 15 H 14 FN 3 O 3

formula text :

C15H14FN3O3

cas num :

78755-81-4

2020 USD :

2021 USD :

102 USD

alt names :

Ro 15-1788

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage