1328/10 | Tocris Bioscience 1328/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

1328/10

catalog :

1328/10

quantity :

10 mg (also 50 mg)

price :

130 USD

more info or order :

Tocris Bioscience product webpage

citations: 8

Reference
Brodnik Z, Batra A, Oleson E, Espana R. Local GABAA Receptor-Mediated Suppression of Dopamine Release within the Nucleus Accumbens. ACS Chem Neurosci. 2019;10:1978-1985 pubmed publisher
Maya Mendoza A, Moudry P, Merchut Maya J, Lee M, Strauss R, Bartek J. High speed of fork progression induces DNA replication stress and genomic instability. Nature. 2018;559:279-284 pubmed publisher
Joensuu T, Tegelberg S, Reinmaa E, Segerstrale M, Hakala P, Pehkonen H, et al. Gene expression alterations in the cerebellum and granule neurons of Cstb(-/-) mouse are associated with early synaptic changes and inflammation. PLoS ONE. 2014;9:e89321 pubmed publisher
Heidelberg L, Warren J, Fisher J. SB-205384 is a positive allosteric modulator of recombinant GABAA receptors containing rat ?3, ?5, or ?6 subunit subtypes coexpressed with ?3 and ?2 subunits. J Pharmacol Exp Ther. 2013;347:235-41 pubmed publisher
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher
Carlile E, Shirachi D, Quock R. An anxiolytic-like effect of hyperbaric oxygen in the mouse light/dark exploration test. Life Sci. 2012;90:267-71 pubmed publisher
Leppä E, Linden A, Vekovischeva O, Swinny J, Rantanen V, Toppila E, et al. Removal of GABA(A) receptor ?2 subunits from parvalbumin neurons causes wide-ranging behavioral alterations. PLoS ONE. 2011;6:e24159 pubmed publisher
Linden A, Schmitt U, Leppä E, Wulff P, Wisden W, Lüddens H, et al. Ro 15-4513 Antagonizes Alcohol-Induced Sedation in Mice Through ???2-type GABA(A) Receptors. Front Neurosci. 2011;5:3 pubmed publisher

product information

master code :

1328

SKU :

1328/10

product name :

Flumazenil

unit size :

10 mg (also 50 mg)

description :

Benzodiazepine antagonist

target :

GABA-A Receptor Benzodiazepines

category :

Small Molecules

purity :

99%

observed molecular weight :

303.29

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Flumazenil is a benzodiazepine antagonist, non-selective for 1, 2, 3 or 5-containing GABAA receptors. Centrally active upon systemic administration in vivo . Also inhibits repressor element-1 silencing transcription factor (REST) by targeting degradation.

top caption :

Benzodiazepine antagonist

extended description :

Benzodiazepine antagonist

chemical name text :

8-Fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, ethyl ester

formula :

C15H14FN3O3

formula text :

C15H14FN3O3

cas num :

78755-81-4

USD :

130 USD

product details :

Benzodiazepine antagonist

alt names :

Ro 15-1788

storage :

Store at +4░C

more info or order :

Tocris Bioscience product webpage