product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
RX 821002 hydrochloride
catalog :
1324
quantity :
10 mg (also 50 mg)
price :
75 USD
more info or order :
citations: 7
Reference
Uchański T, Zögg T, Yin J, Yuan D, Wohlkonig A, Fischer B, et al. An improved yeast surface display platform for the screening of nanobody immune libraries. Sci Rep. 2019;9:382 pubmed publisher
Staedtke V, Bai R, Kim K, Darvas M, DAVILA M, Riggins G, et al. Disruption of a self-amplifying catecholamine loop reduces cytokine release syndrome. Nature. 2018;564:273-277 pubmed publisher
Li Y, Lucas Osma A, Black S, Bandet M, Stephens M, Vavrek R, et al. Pericytes impair capillary blood flow and motor function after chronic spinal cord injury. Nat Med. 2017;23:733-741 pubmed publisher
Alves F, Crestani C, Resstel L, Correa F. Both ?1- and ?2-adrenoceptors in the insular cortex are involved in the cardiovascular responses to acute restraint stress in rats. PLoS ONE. 2014;9:e83900 pubmed publisher
Hott S, Gomes F, Fabri D, Reis D, Crestani C, Correa F, et al. Both ?1- and ?1-adrenoceptors in the bed nucleus of the stria terminalis are involved in the expression of conditioned contextual fear. Br J Pharmacol. 2012;167:207-21 pubmed publisher
Deupree J, Burke W, Bylund D. Alpha-2 adrenergic-induced changes in rectal temperature in adult and 13-day old rats following acute and repeated desipramine administration. BMC Pharmacol. 2008;8:17 pubmed publisher
Crestani C, Alves F, Resstel L, Correa F. Both alpha1 and alpha2-adrenoceptors mediate the cardiovascular responses to noradrenaline microinjected into the bed nucleus of the stria terminal of rats. Br J Pharmacol. 2008;153:583-90 pubmed
product information
brand :
Tocris
master code :
1324
SKU :
1324/10
product name :
RX 821002 hydrochloride
description :
Potent, selective 2D antagonist
target :
Adrenergic alpha-2 Receptor Antagonists
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
99%
observed molecular weight :
270.72
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Potent, selective 2-adrenoceptor antagonist with very low affinity for imidazoline sites. Displays selectivity for the 2D over the 2A subtypes (pKd values are 9.7 and 8.2 respectively).
catalog number base :
1324
product keywords :
Potent selective 2D-adrenoceptor alpha2D-adrenoceptor a2d-adrenoceptor 2d-adrenergic alpha2d-adrenergic a2d-adrenergic antagonists Receptors RX821002 hydrochloride Adrenergic Alpha-2 Receptors 1324,
extended description :
Potent, selective 2D antagonist
chemical name text :
2-(2,3-Dihydro-2-methoxy-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole hydrochloride
formula :
C 12 H 14 N 2 O 3 .HCl
formula text :
C12H14N2O3.HCl
cas num :
109544-45-8
2020 USD :
72
2021 USD :
75 USD
storage :
Desiccate at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK