product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
WY 14643
catalog :
1312
quantity :
10 mg (also 50 mg)
price :
63 USD
more info or order :
citations: 12
Reference |
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Smith D, Martinelli R, Besra G, Illarionov P, Szatmari I, Brazda P, et al. Identification and characterization of a novel anti-inflammatory lipid isolated from Mycobacterium vaccae, a soil-derived bacterium with immunoregulatory and stress resilience properties. Psychopharmacology (Berl). 2019;: pubmed publisher
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Bumpus N, Johnson E. 5-Aminoimidazole-4-carboxyamide-ribonucleoside (AICAR)-stimulated hepatic expression of Cyp4a10, Cyp4a14, Cyp4a31, and other peroxisome proliferator-activated receptor α-responsive mouse genes is AICAR 5'-monophosphate-dependent and AMP-activated pro. J Pharmacol Exp Ther. 2011;339:886-95 pubmed publisher
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Lee G, Kim N, Zhao Z, Cha B, Kim Y. Peroxisomal-proliferator-activated receptor alpha activates transcription of the rat hepatic malonyl-CoA decarboxylase gene: a key regulation of malonyl-CoA level. Biochem J. 2004;378:983-90 pubmed
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product information
brand :
Tocris
master code :
1312
SKU :
1312/10
product name :
WY 14643
description :
Selective PPAR agonist
target :
PPAR alpha Receptor Agonists
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
98%
observed molecular weight :
323.8
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Selective PPAR agonist (EC50 values are 0.63, 32 and 100 u M at PPAR , PPAR and PPAR respectively). Negatively inhibits NF- B transcriptional activity and decreases the inflammatory response in vitro and in vivo .
catalog number base :
1312
product keywords :
Selective PPAR PPARalpha agonists Peroxisome-Proliferator Receptors PPARs WY14643 PPARalpha Receptors 1312,
extended description :
Selective PPAR agonist
chemical name text :
[[4-Chloro-6-[(2,3-dimethylphenyl)amino]-2-pyrimidinyl]thio]acetic acid
formula :
C 14 H 14 ClN 3 O 2 S
formula text :
C14H14ClN3O2S
cas num :
50892-23-4
2020 USD :
61
2021 USD :
63 USD
storage :
Store at RT
more info or order :
company information

Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com800-343-7475
headquarters: UK
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