product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
UCL 1684
catalog :
1310
quantity :
5 mg
price :
205 USD
more info or order :
citations: 13
Reference |
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Szollosi A, Nenquin M, Aguilar Bryan L, Bryan J, Henquin J. Glucose stimulates Ca2+ influx and insulin secretion in 2-week-old beta-cells lacking ATP-sensitive K+ channels. J Biol Chem. 2007;282:1747-56 pubmed
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product information
brand :
Tocris
master code :
1310
SKU :
1310/5
product name :
UCL 1684
description :
Highly potent KCa2 (SK) channel blocker
target :
Ca2+-Activated Potassium Channel Blockers
category :
Small Molecules
unit size :
5 mg
purity :
97%
observed molecular weight :
654.44
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Highly potent, non-peptidic blocker of the apamin-sensitive Ca2+-activated K+ channel (KCa2.1) (IC50 = 3 nM in rat sympathetic neurons). Blocks hKCa2.1 and rKCa2.2 channels expressed in HEK 293 cells with IC50 values of 762 and 364 pM respectively.
catalog number base :
1310
product keywords :
potent blockers SKCa Potassium Channels K+ ca2+-activated ca2+-dependent SK1 SK2 UCL1684 Ca2+-Activated Potassium Channels 1310,
extended description :
Highly potent KCa2 (SK) channel blocker
chemical name text :
6,12,19,20,25,26-Hexahydro-5,27:13,18:21,24-trietheno-11,7-metheno-7H-dibenzo [b,n] [1,5,12,16]tetraazacyclotricosine-5,13-diium dibromide
formula :
C 34 H 30 Br 2 N 4
formula text :
C34H30Br2N4
cas num :
199934-16-2
2020 USD :
197
2021 USD :
205 USD
storage :
Desiccate at RT
more info or order :
company information

Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com800-343-7475
headquarters: UK
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