1302/10 | Tocris Bioscience 1302/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

1302/10

catalog :

1302/10

quantity :

10 mg (also 50 mg)

price :

293 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher
Broadstock M, Austin P, Betts M, Duty S. Antiparkinsonian potential of targeting group III metabotropic glutamate receptor subtypes in the rodent substantia nigra pars reticulata. Br J Pharmacol. 2012;165:1034-45 pubmed publisher

product information

master code :

1302

SKU :

1302/10

product name :

(S)-3,4-DCPG

unit size :

10 mg (also 50 mg)

description :

Potent and selective mGlu8a agonist

target :

Group III mGluR Agonists

category :

Small Molecules

purity :

98%

observed molecular weight :

239.18

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

( S )-3,4-DCPG is a potent, selective mGlu8a agonist (EC50 = 31 nM). Displays 100-fold selectivity over mGlu1-7 and displays little or no activity at NMDA and kainate receptors. Increases c-Fos expression in stress-related brain areas following systemic administration in mice in vivo . Also potent anticonvulsant in mice in vivo . . Caged ( S )-3,4-DCPG, Racemate and R-enantiomer also available.

top caption :

Potent and selective mGlu8a agonist

extended description :

Potent and selective mGlu8a agonist

chemical name text :

(S)-3,4-Dicarboxyphenylglycine

formula :

C10H9NO6

formula text :

C10H9NO6

cas num :

201730-11-2

USD :

293 USD

product details :

Potent and selective mGlu8a agonist

alt names :

UBP 1109

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage