1296/10 | Tocris Bioscience 1296/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

1296/10

catalog :

1296/10

quantity :

10 mg (also 50 mg)

price :

261 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher

product information

master code :

1296

SKU :

1296/10

product name :

CI 966 hydrochloride

unit size :

10 mg (also 50 mg)

description :

Selective inhibitor of GAT-1

target :

GABA Transporter Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

509.87

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

CI 966 hydrochloride is a selective inhibitor of the GABA transporter GAT-1 (IC50 values are 0.26 and 1.2 u M at cloned human and rat GAT-1 respectively). Displays over 200-fold selectivity over GAT-2 and GAT-3. Centrally active upon systemic administration in vivo . Anticonvulsive and neuroprotective.

top caption :

Selective inhibitor of GAT-1

extended description :

Selective inhibitor of GAT-1

chemical name text :

1-[2-[bis[4-(Trifluoromethyl)phenyl]methoxy]ethyl]-1,2,5,6-tetrahydropyridine-3-carboxylic acid hydrochloride

formula :

C23H21F6NO3.HCl

formula text :

C23H21F6NO3.HCl

cas num :

110283-66-4

USD :

261 USD

product details :

Selective inhibitor of GAT-1

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage