beta-Lapachone | Tocris Bioscience 1293/50 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

beta-Lapachone

catalog :

1293/50

quantity :

50 mg

price :

459 USD

citations: 1

Reference
Joshi A, Iyengar R, Joo J, Li Harms X, Wright C, Marino R, et al. Nuclear ULK1 promotes cell death in response to oxidative stress through PARP1. Cell Death Differ. 2016;23:216-30 pubmed publisher

product information

brand :

Tocris

master code :

1293

SKU :

1293/50

product name :

beta-Lapachone

description :

DNA topoisomerase I inhibitor

target :

DNA Topoisomerase Inhibitors

category :

Small Molecules

unit size :

50 mg

purity :

98%

observed molecular weight :

242.27

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

-Lapachone is a DNA topoisomerase I inhibitor. Exhibits a different inhibitory mechanism to camptothecin (Cat. No. 1100). Induces apoptosis in a variety of cell lines, including prostate cancer and promyelocytic leukemia cells; blocks the cell cycle in G0/G1. Also has effects on DNA topoisomerase II, NF- B, AP-1, and JNK.

catalog number base :

1293

extended description :

DNA topoisomerase I inhibitor

chemical name text :

3,4-Dihydro-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5,6-dione

formula :

C 15 H 14 O 3

formula text :

C15H14O3

cas num :

4707-32-8

USD 2021 :

441

USD 2022 :

459 USD

product details :

DNA topoisomerase I inhibitor

storage :

Store at +4°C