beta-Lapachone | Tocris Bioscience 1293/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

beta-Lapachone

catalog :

1293/10

quantity :

10 mg

price :

116 USD

citations: 1

Reference
Joshi A, Iyengar R, Joo J, Li Harms X, Wright C, Marino R, et al. Nuclear ULK1 promotes cell death in response to oxidative stress through PARP1. Cell Death Differ. 2016;23:216-30 pubmed publisher

product information

brand :

Tocris

master code :

1293

SKU :

1293/10

product name :

beta-Lapachone

unit size :

10 mg

description :

mTOR inhibitor; immunosuppressant

target :

DNA Topoisomerase Inhibitors

category :

Small Molecules

purity :

98%

storage :

Store at +4°C

observed molecular weight :

242.27

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

-Lapachone is a DNA topoisomerase I inhibitor. Exhibits a different inhibitory mechanism to camptothecin (Cat. No. 1100). Induces apoptosis in a variety of cell lines, including prostate cancer and promyelocytic leukemia cells; blocks the cell cycle in G0/G1. Also has effects on DNA topoisomerase II, NF- B, AP-1, and JNK.

extended description :

DNA topoisomerase I inhibitor

chemical name text :

3,4-Dihydro-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5,6-dione

formula :

C 15 H 14 O 3

formula text :

C15H14O3

cas num :

4707-32-8

USD :

110

Jul-22 :

116 USD

product details :

DNA topoisomerase I inhibitor

sizes available :

10 mg (also 50 mg)