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company name :
Tocris Bioscience
product type :
chemical
product name :
1292/1
catalog :
1292/1
quantity :
1 mg
price :
387 USD
more info or order :
citations: 54
Reference
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product information
master code :
1292
SKU :
1292/1
product name :
Rapamycin
unit size :
1 mg
description :
mTOR inhibitor; immunosuppressant
target :
mTOR Inhibitors
category :
Small Molecules
purity :
98%
observed molecular weight :
914.18
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Rapamycin is an antifungal and immunosuppressant. Rapamycin is a specific inhibitor of mTOR (mammalian target of rapamycin); complexes with FKBP-12 and binds mTOR inhibiting its activity. Rapamycin inhibits interleukin-2-induced phosphorylation and activation of p70 S6 kinase and induces autophagy in yeast and mammalian cell lines. Rapamycin drives hPSC differentiation to mesendoderm and blood progenitor cells. Also used as a chemical dimerizer; rapamycin and GA3-AM chemically inducible dimerization systems are orthogonal. Inhibits MERS-CoV infection of Huh7 cells in a plaque reduction assay. Enhances lentiviral transduction of hematopoietic stem cells.
top caption :
mTOR inhibitor; immunosuppressant
extended description :
mTOR inhibitor; immunosuppressant
chemical name text :
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-ep
formula :
C51H79NO13
formula text :
C51H79NO13
cas num :
53123-88-9
USD :
387 USD
product details :
mTOR inhibitor; immunosuppressant
storage :
Store at -20░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK