product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
1256/10
catalog :
1256/10
quantity :
10 mg (also 50 mg)
price :
159 USD
more info or order :
citations: 7
Reference
Bernier L, Bohlen C, York E, Choi H, Kamyabi A, Dissing Olesen L, et al. Nanoscale Surveillance of the Brain by Microglia via cAMP-Regulated Filopodia. Cell Rep. 2019;27:2895-2908.e4 pubmed publisher
Zhang H, Patel A, Wang Y, Zhang Y, Kathawala R, Qiu L, et al. The BTK Inhibitor Ibrutinib (PCI-32765) Overcomes Paclitaxel Resistance in ABCB1- and ABCC10-Overexpressing Cells and Tumors. Mol Cancer Ther. 2017;16:1021-1030 pubmed publisher
Kathawala R, Wei L, Anreddy N, Chen K, Patel A, Alqahtani S, et al. The small molecule tyrosine kinase inhibitor NVP-BHG712 antagonizes ABCC10-mediated paclitaxel resistance: a preclinical and pharmacokinetic study. Oncotarget. 2015;6:510-21 pubmed
Ahmad N, Rahim R, Mat I. Catharanthus roseus Aqueous Extract is Cytotoxic to Jurkat Leukaemic T-cells but Induces the Proliferation of Normal Peripheral Blood Mononuclear Cells. Trop Life Sci Res. 2010;21:101-13 pubmed
Kathawala R, Sodani K, Chen K, Patel A, Abuznait A, Anreddy N, et al. Masitinib antagonizes ATP-binding cassette subfamily C member 10-mediated paclitaxel resistance: a preclinical study. Mol Cancer Ther. 2014;13:714-23 pubmed publisher
Musiwaro P, Smith M, Manifava M, Walker S, Ktistakis N. Characteristics and requirements of basal autophagy in HEK 293 cells. Autophagy. 2013;9:1407-17 pubmed publisher
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher
product information
master code :
1256
SKU :
1256/10
product name :
Vinblastine sulfate
unit size :
10 mg (also 50 mg)
description :
Disrupts microtubules
target :
Microtubule Binding Compounds
category :
Small Molecules
purity :
95%
observed molecular weight :
909.06
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Vinblastine sulfate is a anticancer agent; microtubule disrupter. Induces apoptosis in cultured hepatocytes and human lymphoma cells. Shown to inhibit autophagosome maturation.
top caption :
Disrupts microtubules
extended description :
Disrupts microtubules
chemical name text :
Vincaleukoblastine
formula :
C46H58N4O9.H2SO4
formula text :
C46H58N4O9.H2SO4
cas num :
143-67-9
USD :
159 USD
product details :
Disrupts microtubules
storage :
Store at -20░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK