product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
CGP 46381
catalog :
1247
quantity :
10 mg (also 50 mg)
price :
212 USD
more info or order :
citations: 5
Reference
Oberlander J, Woolley C. 17β-Estradiol Acutely Potentiates Glutamatergic Synaptic Transmission in the Hippocampus through Distinct Mechanisms in Males and Females. J Neurosci. 2016;36:2677-90 pubmed publisher
Cheng Z, Wang X, Schmid K, Han Y, Han X, Tang H, et al. GABAB receptor antagonist CGP46381 inhibits form-deprivation myopia development in guinea pigs. Biomed Res Int. 2015;2015:207312 pubmed publisher
Lee C, Sherman S. Intrinsic modulators of auditory thalamocortical transmission. Hear Res. 2012;287:43-50 pubmed publisher
Pacey L, Tharmalingam S, Hampson D. Subchronic administration and combination metabotropic glutamate and GABAB receptor drug therapy in fragile X syndrome. J Pharmacol Exp Ther. 2011;338:897-905 pubmed publisher
Costa C, Belcastro V, Tozzi A, Di Filippo M, Tantucci M, Siliquini S, et al. Electrophysiology and pharmacology of striatal neuronal dysfunction induced by mitochondrial complex I inhibition. J Neurosci. 2008;28:8040-52 pubmed publisher
product information
brand :
Tocris
master code :
1247
SKU :
1247/10
product name :
CGP 46381
description :
Selective GABAB antagonist; brain penetrant
target :
GABA-B Receptor Antagonists
category :
Small Molecules
unit size :
10 mg (also 50 mg)
observed molecular weight :
219.26
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Brain penetrant, selective GABAB receptor antagonist (IC50 = 4.9 M).
catalog number base :
1247
product keywords :
Brain penetrant selective GABAB antagonist Receptors CGP46381 GABAB Receptors 1247,
extended description :
Selective GABAB antagonist; brain penetrant
chemical name text :
(3-Aminopropyl)(cyclohexylmethyl)phosphinic acid
formula :
C 10 H 22 NO 2 P
formula text :
C10H22NO2P
cas num :
123691-14-5
2020 USD :
205
2021 USD :
212 USD
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK