product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
1245/10
catalog :
1245/10
quantity :
10 mg (also 50 mg)
price :
261 USD
more info or order :
citations: 11
Reference |
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Milenkovic I, Witte M, Turecek R, Heinrich M, Reinert T, Rubsamen R. Development of chloride-mediated inhibition in neurons of the anteroventral cochlear nucleus of gerbil (Meriones unguiculatus). J Neurophysiol. 2007;98:1634-44 pubmed
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Wood M, Murkitt K, Rice S, Testa T, Punia P, Stammers M, et al. The human GABA(B1b) and GABA(B2) heterodimeric recombinant receptor shows low sensitivity to phaclofen and saclofen. Br J Pharmacol. 2000;131:1050-4 pubmed
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product information
master code :
1245
SKU :
1245/10
product name :
CGP 35348
unit size :
10 mg (also 50 mg)
description :
Selective GABAB antagonist; brain penetrant
target :
GABA-B Receptor Antagonists
category :
Small Molecules
observed molecular weight :
225.22
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
CGP 35348 is a selective, brain penetrant GABAB receptor antagonist (IC50 = 34 u M as measured in rat cortical membranes). Has higher affinity for postsynaptic versus presynaptic receptors.
top caption :
Selective GABAB antagonist; brain penetrant
extended description :
Selective GABAB antagonist; brain penetrant
chemical name text :
(3-Aminopropyl)(diethoxymethyl)phosphinic acid
formula :
C8H20NO4P
formula text :
C8H20NO4P
cas num :
123690-79-9
USD :
261 USD
product details :
Selective GABAB antagonist; brain penetrant
storage :
Store at RT
more info or order :
company information

Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com800-343-7475
headquarters: UK
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