product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
1243/10
catalog :
1243/10
quantity :
10 mg (also 50 mg)
price :
380 USD
more info or order :
citations: 11
Reference |
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Zapata A, Kivell B, Han Y, Javitch J, Bolan E, Kuraguntla D, et al. Regulation of dopamine transporter function and cell surface expression by D3 dopamine receptors. J Biol Chem. 2007;282:35842-54 pubmed
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Basso A, Gallagher K, Bratcher N, Brioni J, Moreland R, Hsieh G, et al. Antidepressant-like effect of D(2/3) receptor-, but not D(4) receptor-activation in the rat forced swim test. Neuropsychopharmacology. 2005;30:1257-68 pubmed
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Clemens S, Hochman S. Conversion of the modulatory actions of dopamine on spinal reflexes from depression to facilitation in D3 receptor knock-out mice. J Neurosci. 2004;24:11337-45 pubmed
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Zhang L, Lou D, Jiao H, Zhang D, Wang X, Xia Y, et al. Cocaine-induced intracellular signaling and gene expression are oppositely regulated by the dopamine D1 and D3 receptors. J Neurosci. 2004;24:3344-54 pubmed
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product information
master code :
1243
SKU :
1243/10
product name :
(+)-PD 128907 hydrochloride
unit size :
10 mg (also 50 mg)
description :
High affinity D3 agonist (D3 D2 D4)
target :
Dopamine D3 Receptor Agonists
category :
Small Molecules
purity :
98%
observed molecular weight :
285.77
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
(+)-PD 128907 hydrochloride is a high affinity D3 dopamine receptor agonist (Ki = 2.3 nM). Displays 18 - 200-fold selectivity over other dopamine receptor subtypes.
top caption :
High affinity D3 agonist (D3 D2 D4)
extended description :
High affinity D3 agonist (D3 D2 D4)
chemical name text :
(4aR,10bR)-3,4a,4,10b-Tetrahydro-4-propyl-2H,5H-[1]benzopyrano-[4,3-b]-1,4-oxazin-9-ol hydrochloride
formula :
C14H19NO3.HCl
formula text :
C14H19NO3.HCl
cas num :
300576-59-4
USD :
380 USD
product details :
High affinity D3 agonist (D3 D2 D4)
storage :
Store at +4░C
more info or order :
company information

Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com800-343-7475
headquarters: UK
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