SB 216641 hydrochloride | Tocris Bioscience 1242 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SB 216641 hydrochloride

catalog :

1242

quantity :

10 mg (also 50 mg)

price :

238 USD

more info or order :

Tocris Bioscience product webpage

citations: 5

Reference
Krishnan B. Amygdala-Hippocampal Phospholipase D (PLD) Signaling As Novel Mechanism of Cocaine-Environment Maladaptive Conditioned Responses. Int J Neuropsychopharmacol. 2016;: pubmed publisher
Soll C, Riener M, Oberkofler C, Hellerbrand C, Wild P, DeOliveira M, et al. Expression of serotonin receptors in human hepatocellular cancer. Clin Cancer Res. 2012;18:5902-10 pubmed publisher
Murray K, Stephens M, Rank M, D Amico J, Gorassini M, Bennett D. Polysynaptic excitatory postsynaptic potentials that trigger spasms after spinal cord injury in rats are inhibited by 5-HT1B and 5-HT1F receptors. J Neurophysiol. 2011;106:925-43 pubmed publisher
Dunbar M, Tran M, Whelan P. Endogenous extracellular serotonin modulates the spinal locomotor network of the neonatal mouse. J Physiol. 2010;588:139-56 pubmed publisher
Watakabe A, Komatsu Y, Sadakane O, Shimegi S, Takahata T, Higo N, et al. Enriched expression of serotonin 1B and 2A receptor genes in macaque visual cortex and their bidirectional modulatory effects on neuronal responses. Cereb Cortex. 2009;19:1915-28 pubmed publisher

product information

brand :

Tocris

master code :

1242

SKU :

1242/10

product name :

SB 216641 hydrochloride

description :

Selective h5-HT1B antagonist

target :

5-HT1B Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

523.03

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

A selective h5-HT1B antagonist with approximately 25-fold selectivity over h5-HT1D and little or no affinity for a range of other receptor types.

catalog number base :

1242

product keywords :

Selective h5-HT1B antagonist Serotonin Receptors SB216641 hydrochloride GlaxoSmithKline GSK 5-HT1B Receptors 1242,

extended description :

Selective h5-HT1B antagonist

chemical name text :

N-[3-[3-(Dimethylamino)ethoxy]-4-methoxyphenyl]-2 -methyl-4 -(5-methyl-1,2,4-oxadiazol-3-yl)-[1,1 -biphenyl]-4-carboxamide hydrochloride

formula :

C 28 H 30 N 4 O 4 .HCl

formula text :

C28H30N4O4.HCl

cas num :

193611-67-5

2020 USD :

228

2021 USD :

238 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage