product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
1242/10
catalog :
1242/10
quantity :
10 mg (also 50 mg)
price :
299 USD
more info or order :
citations: 6
Reference
Krishnan B. Amygdala-Hippocampal Phospholipase D (PLD) Signaling As Novel Mechanism of Cocaine-Environment Maladaptive Conditioned Responses. Int J Neuropsychopharmacol. 2016;: pubmed publisher
Soll C, Riener M, Oberkofler C, Hellerbrand C, Wild P, DeOliveira M, et al. Expression of serotonin receptors in human hepatocellular cancer. Clin Cancer Res. 2012;18:5902-10 pubmed publisher
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher
Murray K, Stephens M, Rank M, D Amico J, Gorassini M, Bennett D. Polysynaptic excitatory postsynaptic potentials that trigger spasms after spinal cord injury in rats are inhibited by 5-HT1B and 5-HT1F receptors. J Neurophysiol. 2011;106:925-43 pubmed publisher
Dunbar M, Tran M, Whelan P. Endogenous extracellular serotonin modulates the spinal locomotor network of the neonatal mouse. J Physiol. 2010;588:139-56 pubmed publisher
Watakabe A, Komatsu Y, Sadakane O, Shimegi S, Takahata T, Higo N, et al. Enriched expression of serotonin 1B and 2A receptor genes in macaque visual cortex and their bidirectional modulatory effects on neuronal responses. Cereb Cortex. 2009;19:1915-28 pubmed publisher
product information
master code :
1242
SKU :
1242/10
product name :
SB 216641 hydrochloride
unit size :
10 mg (also 50 mg)
description :
Selective h5-HT1B antagonist
target :
5-HT1B Receptor Antagonists
category :
Small Molecules
purity :
98%
observed molecular weight :
523.03
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
SB 216641 hydrochloride is a selective h5-HT1B antagonist with approximately 25-fold selectivity over h5-HT1D and little or no affinity for a range of other receptor types.
top caption :
Selective h5-HT1B antagonist
extended description :
Selective h5-HT1B antagonist
chemical name text :
N-[3-[3-(Dimethylamino)ethoxy]-4-methoxyphenyl]-2 -methyl-4 -(5-methyl-1,2,4-oxadiazol-3-yl)-[1,1 -biphenyl]-4-carboxamide hydrochloride
formula :
C28H30N4O4.HCl
formula text :
C28H30N4O4.HCl
cas num :
193611-67-5
USD :
299 USD
product details :
Selective h5-HT1B antagonist
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK