product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Cyclopiazonic acid
catalog :
1235
quantity :
10 mg (also 50 mg)
price :
156 USD
more info or order :
citations: 15
Reference
Atakpa P, Thillaiappan N, Mataragka S, Prole D, Taylor C. IP3 Receptors Preferentially Associate with ER-Lysosome Contact Sites and Selectively Deliver Ca2+ to Lysosomes. Cell Rep. 2018;25:3180-3193.e7 pubmed publisher
Morais T, Coelho D, Vaz S, Sebastião A, Valente C. Glycine Receptor Activation Impairs ATP-Induced Calcium Transients in Cultured Cortical Astrocytes. Front Mol Neurosci. 2017;10:444 pubmed publisher
Chai H, Diaz Castro B, Shigetomi E, Monte E, Octeau J, Yu X, et al. Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence. Neuron. 2017;95:531-549.e9 pubmed publisher
Li L, Pan Z, Huang X, Wu B, Li T, Kang M, et al. Junctophilin 3 expresses in pancreatic beta cells and is required for glucose-stimulated insulin secretion. Cell Death Dis. 2016;7:e2275 pubmed publisher
Fransen P, Van Hove C, Leloup A, Martinet W, De Meyer G, Lemmens K, et al. Dissecting out the complex Ca2+-mediated phenylephrine-induced contractions of mouse aortic segments. PLoS ONE. 2015;10:e0121634 pubmed publisher
Elgueta C, Vielma A, Palacios A, Schmachtenberg O. Acetylcholine induces GABA release onto rod bipolar cells through heteromeric nicotinic receptors expressed in A17 amacrine cells. Front Cell Neurosci. 2015;9:6 pubmed publisher
Zhu M, Sung T, O Driscoll K, Koh S, Sanders K. Intracellular Ca(2+) release from endoplasmic reticulum regulates slow wave currents and pacemaker activity of interstitial cells of Cajal. Am J Physiol Cell Physiol. 2015;308:C608-20 pubmed publisher
Alzayady K, Chandrasekhar R, Yule D. Fragmented inositol 1,4,5-trisphosphate receptors retain tetrameric architecture and form functional Ca2+ release channels. J Biol Chem. 2013;288:11122-34 pubmed publisher
McQuail J, Davis K, Miller F, Hampson R, Deadwyler S, Howlett A, et al. Hippocampal G?q/?? but not G?o-coupled receptors are altered in aging. Neuropharmacology. 2013;70:63-73 pubmed publisher
Earls L, Bayazitov I, Fricke R, Berry R, Illingworth E, Mittleman G, et al. Dysregulation of presynaptic calcium and synaptic plasticity in a mouse model of 22q11 deletion syndrome. J Neurosci. 2010;30:15843-55 pubmed publisher
Grey K, Burrell B. Co-induction of LTP and LTD and its regulation by protein kinases and phosphatases. J Neurophysiol. 2010;103:2737-46 pubmed publisher
Patel J, Witkovsky P, Avshalumov M, Rice M. Mobilization of calcium from intracellular stores facilitates somatodendritic dopamine release. J Neurosci. 2009;29:6568-79 pubmed publisher
Choi S, Ahn D, Lee Y. Comparison of contractile mechanisms of sphingosylphosphorylcholine and sphingosine-1-phosphate in rabbit coronary artery. Cardiovasc Res. 2009;82:324-32 pubmed publisher
Eder A, Bading H. Calcium signals can freely cross the nuclear envelope in hippocampal neurons: somatic calcium increases generate nuclear calcium transients. BMC Neurosci. 2007;8:57 pubmed
Kumar A, Foster T. Enhanced long-term potentiation during aging is masked by processes involving intracellular calcium stores. J Neurophysiol. 2004;91:2437-44 pubmed
product information
brand :
Tocris
master code :
1235
SKU :
1235/10
product name :
Cyclopiazonic acid
description :
Inhibitor of SERCA ATPase
target :
Ca2+-ATPase Inhibitors
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
98%
observed molecular weight :
336.39
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Cell-permeable, reversible inhibitor of sarcoplasmic reticulum Ca2+-ATPase.
catalog number base :
1235
product keywords :
inhibitors inhibits SERCA ATPase Ca2+ modulators Ca2+-ATPase Signaling Signalling Calcium P-Type ATPases Calcium-ATPase Ion Transporters Pumps -Cyclopiazonic acid alpha-Cyclopiazonic a-Cyclopiazonic acid Ca2+-ATPase 1235,
extended description :
Inhibitor of SERCA ATPase
chemical name text :
(6aR,11aS,11bR)-rel-10-Acetyl-2,6,6a,7,11a,11b-hexahydro-7,7-dimethyl-9H-pyrrolo[1 ,2 :2,3]isoindolo[4,5,6-cd]indol-9-one
formula :
C 20 H 20 N 2 O 3
formula text :
C20H20N2O3
cas num :
18172-33-3
2020 USD :
152
2021 USD :
156 USD
alt names :
-Cyclopiazonic acid
storage :
Store at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK