1234/10 | Tocris Bioscience 1234/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

1234/10

catalog :

1234/10

quantity :

10 mg

price :

209 USD

more info or order :

Tocris Bioscience product webpage

citations: 11

Reference
Megia Fernandez A, Mills B, Michels C, Chankeshwara S, Krstajic N, Haslett C, et al. Bimodal fluorogenic sensing of matrix proteolytic signatures in lung cancer. Org Biomol Chem. 2018;16:8056-8063 pubmed publisher
Goldberg J, Currais A, Prior M, Fischer W, Chiruta C, RATLIFF E, et al. The mitochondrial ATP synthase is a shared drug target for aging and dementia. Aging Cell. 2018;17: pubmed publisher
Wajih N, Basu S, Jailwala A, Kim H, Ostrowski D, Perlegas A, et al. Potential therapeutic action of nitrite in sickle cell disease. Redox Biol. 2017;12:1026-1039 pubmed publisher
Hou L, Liu K, Li Y, Ma S, Ji X, Liu L. Necrotic pyknosis is a morphologically and biochemically distinct event from apoptotic pyknosis. J Cell Sci. 2016;129:3084-90 pubmed publisher
Cahalan S, Lukacs V, Ranade S, Chien S, Bandell M, Patapoutian A. Piezo1 links mechanical forces to red blood cell volume. elife. 2015;4: pubmed publisher
Diaz M, Li N, Lee H, Adamo L, Evans S, Willey H, et al. Biomechanical forces promote blood development through prostaglandin E2 and the cAMP-PKA signaling axis. J Exp Med. 2015;212:665-80 pubmed publisher
Schöndorf D, Aureli M, McAllister F, Hindley C, Mayer F, Schmid B, et al. iPSC-derived neurons from GBA1-associated Parkinson's disease patients show autophagic defects and impaired calcium homeostasis. Nat Commun. 2014;5:4028 pubmed publisher
Harper M, Poole A. Chloride channels are necessary for full platelet phosphatidylserine exposure and procoagulant activity. Cell Death Dis. 2013;4:e969 pubmed publisher
Yung M, Chan D, Liu V, Yao K, Ngan H. Activation of AMPK inhibits cervical cancer cell growth through AKT/FOXO3a/FOXM1 signaling cascade. BMC Cancer. 2013;13:327 pubmed publisher
Cheang W, Wong W, Tian X, Yang Q, Lee H, He G, et al. Endothelial nitric oxide synthase enhancer reduces oxidative stress and restores endothelial function in db/db mice. Cardiovasc Res. 2011;92:267-75 pubmed publisher
Arozarena I, Sanchez Laorden B, Packer L, Hidalgo Carcedo C, Hayward R, Viros A, et al. Oncogenic BRAF induces melanoma cell invasion by downregulating the cGMP-specific phosphodiesterase PDE5A. Cancer Cell. 2011;19:45-57 pubmed publisher

product information

master code :

1234

SKU :

1234/10

product name :

A23187, free acid

unit size :

10 mg

description :

Calcium ionophore

target :

Calcium Signaling Agents

category :

Small Molecules

purity :

98%

observed molecular weight :

523.63

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

A23187, free acid is a calcium ionophore that induces Ca2+-dependent cell death by increasing intracellular calcium concentration. Promotes intracelllular ROS generation and platelet particle formation (fragmentation) in vitro and in vivo . Can be used to induce autophagy in mammalian cells.

top caption :

Calcium ionophore

extended description :

Calcium ionophore

chemical name text :

5-(Methylamino)-2-[[2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)-ethyl]-1,7-dioxaspiro[5.5]undec-2-yl]methyl]-4-benzoxazolecarboxylic acid

formula :

C29H37N3O6

formula text :

C29H37N3O6

cas num :

52665-69-7

USD :

209 USD

product details :

Calcium ionophore

alt names :

Calcimycin

storage :

Store at +4░C

more info or order :

Tocris Bioscience product webpage