product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
1233/1
catalog :
1233/1
quantity :
1 mg (also 5 mg)
price :
158 USD
more info or order :
citations: 27
Reference
Lee H, Stowers R, Chaudhuri O. Volume expansion and TRPV4 activation regulate stem cell fate in three-dimensional microenvironments. Nat Commun. 2019;10:529 pubmed publisher
Penchev V, Chang Y, Begum A, Ewachiw T, Gocke C, Li J, et al. Ezrin Promotes Stem Cell Properties in Pancreatic Ductal Adenocarcinoma. Mol Cancer Res. 2019;17:929-936 pubmed publisher
Zorina Y, Stricker J, Caggiano A, Button D. Human IgM antibody rHIgM22 promotes phagocytic clearance of myelin debris by microglia. Sci Rep. 2018;8:9392 pubmed publisher
Diaz Garcia C, Mongeon R, Lahmann C, Koveal D, Zucker H, Yellen G. Neuronal Stimulation Triggers Neuronal Glycolysis and Not Lactate Uptake. Cell Metab. 2017;26:361-374.e4 pubmed publisher
Nishijima N, Hirai T, Misato K, Aoyama M, Kuroda E, Ishii K, et al. Human Scavenger Receptor A1-Mediated Inflammatory Response to Silica Particle Exposure Is Size Specific. Front Immunol. 2017;8:379 pubmed publisher
Aragon Sanabria V, Pohler S, Eswar V, Bierowski M, Gomez E, Dong C. VE-Cadherin Disassembly and Cell Contractility in the Endothelium are Necessary for Barrier Disruption Induced by Tumor Cells. Sci Rep. 2017;7:45835 pubmed publisher
Tóth A, Zajta E, Csonka K, Vagvolgyi C, Netea M, Gacser A. Specific pathways mediating inflammasome activation by Candida parapsilosis. Sci Rep. 2017;7:43129 pubmed publisher
Lahne M, Li J, Marton R, Hyde D. Actin-Cytoskeleton- and Rock-Mediated INM Are Required for Photoreceptor Regeneration in the Adult Zebrafish Retina. J Neurosci. 2015;35:15612-34 pubmed publisher
Yang M, Liu J, Piao C, Shao J, Du J. ICAM-1 suppresses tumor metastasis by inhibiting macrophage M2 polarization through blockade of efferocytosis. Cell Death Dis. 2015;6:e1780 pubmed publisher
Dobson K, Jackson C, Balakrishnan S, Bellamy T. Caffeine Modulates Vesicle Release and Recovery at Cerebellar Parallel Fibre Terminals, Independently of Calcium and Cyclic AMP Signalling. PLoS ONE. 2015;10:e0125974 pubmed publisher
Chen R, Rato C, Yan Y, Crespillo Casado A, Clarke H, Harding H, et al. G-actin provides substrate-specificity to eukaryotic initiation factor 2α holophosphatases. elife. 2015;4: pubmed publisher
Chambers J, Dalton L, Clarke H, Malzer E, Dominicus C, Patel V, et al. Actin dynamics tune the integrated stress response by regulating eukaryotic initiation factor 2α dephosphorylation. elife. 2015;4: pubmed publisher
Gaume X, Tassin A, Ugrinova I, Mongelard F, Monier K, Bouvet P. Centrosomal nucleolin is required for microtubule network organization. Cell Cycle. 2015;14:902-19 pubmed publisher
López Escobar B, Cano D, Rojas A, De Felipe B, Palma F, Sánchez Alcázar J, et al. The effect of maternal diabetes on the Wnt-PCP pathway during embryogenesis as reflected in the developing mouse eye. Dis Model Mech. 2015;8:157-68 pubmed publisher
Gault W, Enyedi B, Niethammer P. Osmotic surveillance mediates rapid wound closure through nucleotide release. J Cell Biol. 2014;207:767-82 pubmed publisher
Boucrot E, Ferreira A, Almeida Souza L, Debard S, Vallis Y, Howard G, et al. Endophilin marks and controls a clathrin-independent endocytic pathway. Nature. 2015;517:460-5 pubmed publisher
Lee W, Leddy H, Chen Y, Lee S, Zelenski N, McNulty A, et al. Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage. Proc Natl Acad Sci U S A. 2014;111:E5114-22 pubmed publisher
Weidert E, Pohler S, Gomez E, Dong C. Actinomyosin contraction, phosphorylation of VE-cadherin, and actin remodeling enable melanoma-induced endothelial cell-cell junction disassembly. PLoS ONE. 2014;9:e108092 pubmed publisher
Mora R, Roberts R, Arnold D. Recombinant probes reveal dynamic localization of CaMKII? within somata of cortical neurons. J Neurosci. 2013;33:14579-90 pubmed publisher
Nakamura M, Hotta K, Oka K. Raman spectroscopic imaging of the whole Ciona intestinalis embryo during development. PLoS ONE. 2013;8:e71739 pubmed publisher
Lin T, Lu C, Huang S, Wang S. Curcumin inhibits glutamate release from rat prefrontal nerve endings by affecting vesicle mobilization. Int J Mol Sci. 2012;13:9097-109 pubmed publisher
Jeyaraj S, Unger N, Eid A, Mitra S, Paul El Dahdah N, Quilliam L, et al. Cyclic AMP-Rap1A signaling activates RhoA to induce ?(2c)-adrenoceptor translocation to the cell surface of microvascular smooth muscle cells. Am J Physiol Cell Physiol. 2012;303:C499-511 pubmed publisher
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Gjorevski N, Nelson C. Endogenous patterns of mechanical stress are required for branching morphogenesis. Integr Biol (Camb). 2010;2:424-34 pubmed publisher
Gomez E, Chen Q, Gjorevski N, Nelson C. Tissue geometry patterns epithelial-mesenchymal transition via intercellular mechanotransduction. J Cell Biochem. 2010;110:44-51 pubmed publisher
Bose D, Thomas D. The actin cytoskeleton differentially regulates NG115-401L cell ryanodine receptor and inositol 1,4,5-trisphosphate receptor induced calcium signaling pathways. Biochem Biophys Res Commun. 2009;379:594-9 pubmed publisher
product information
master code :
1233
SKU :
1233/1
product name :
Cytochalasin D
unit size :
1 mg (also 5 mg)
description :
Disrupts actin filament function
target :
Actin-related Products
category :
Small Molecules
purity :
95%
observed molecular weight :
507.63
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Cytochalasin D is a potent disruptor of actin filament function. Alters tight junction permeability. Unlike cytochalasin B (Cat. No. 5474), does not inhibit monosaccharide transport across the plasma membrane.
top caption :
Disrupts actin filament function
extended description :
Disrupts actin filament function
chemical name text :
(7S,13E,16S,18R,19E,21R)-21-(Acetyloxy)-7,18-dihydroxy-16,18-dimethyl-10-phenyl[11]cytochalasa-6(12),13,19-triene-1,17-dione
formula :
C30H37NO6
formula text :
C30H37NO6
cas num :
22144-77-0
USD :
158 USD
product details :
Disrupts actin filament function
alt names :
Zygosporin A
storage :
Store at -20░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK