Methotrexate | Tocris Bioscience 1230 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Methotrexate

catalog :

1230

quantity :

100 mg

price :

129 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Kumar N, Afjei R, Massoud T, Paulmurugan R. Comparison of cell-based assays to quantify treatment effects of anticancer drugs identifies a new application for Bodipy-L-cystine to measure apoptosis. Sci Rep. 2018;8:16363 pubmed publisher
Robinson T, Liu J, Vizeacoumar F, Sun T, MacLean N, Egan S, et al. RB1 status in triple negative breast cancer cells dictates response to radiation treatment and selective therapeutic drugs. PLoS ONE. 2013;8:e78641 pubmed publisher

product information

brand :

Tocris

master code :

1230

SKU :

1230/100

product name :

Methotrexate

description :

Cytotoxic agent

target :

Cell Cycle Inhibitors

category :

Small Molecules

unit size :

100 mg

purity :

99%

observed molecular weight :

454.44

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Cytotoxic agent. Inhibits thymidylate synthetase and de novo purine synthesis. Potent folic acid antagonist; inhibits dihydrofolate reductase. Also inhibits Ras carboxyl methylation in DKOB8 cells, leading to decreased p44 and Akt activation.

catalog number base :

1230

product keywords :

Cytotoxic agent Dihydrofolate reductases inhibitors inhibits Cell Cycle DHFR chemotherapeutics Dihydrofolate Reductase Cell Cycle Inhibitors 1230,

extended description :

Cytotoxic agent

chemical name text :

N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid

formula :

C 20 H 22 N 8 O 5

formula text :

C20H22N8O5

cas num :

59-05-2

2020 USD :

124

2021 USD :

129 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage