1230/100 | Tocris Bioscience 1230/100 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

1230/100

catalog :

1230/100

quantity :

100 mg

price :

167 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Kumar N, Afjei R, Massoud T, Paulmurugan R. Comparison of cell-based assays to quantify treatment effects of anticancer drugs identifies a new application for Bodipy-L-cystine to measure apoptosis. Sci Rep. 2018;8:16363 pubmed publisher
Robinson T, Liu J, Vizeacoumar F, Sun T, MacLean N, Egan S, et al. RB1 status in triple negative breast cancer cells dictates response to radiation treatment and selective therapeutic drugs. PLoS ONE. 2013;8:e78641 pubmed publisher
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher

product information

master code :

1230

SKU :

1230/100

product name :

Methotrexate

unit size :

100 mg

description :

Cytotoxic agent

target :

Cell Cycle Inhibitors

category :

Small Molecules

purity :

99%

observed molecular weight :

454.44

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Methotrexate is a cytotoxic agent. Inhibits thymidylate synthetase and de novo purine synthesis. Potent folic acid antagonist; inhibits dihydrofolate reductase. Also inhibits Ras carboxyl methylation in DKOB8 cells, leading to decreased p44 and Akt activation.

top caption :

Cytotoxic agent

extended description :

Cytotoxic agent

chemical name text :

N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid

formula :

C20H22N8O5

formula text :

C20H22N8O5

cas num :

59-05-2

USD :

167 USD

product details :

Cytotoxic agent

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage