product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
1229/10
catalog :
1229/10
quantity :
10 mg
price :
212 USD
more info or order :
citations: 23
Reference |
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Visavadiya N, Keasey M, Razskazovskiy V, Banerjee K, Jia C, Lovins C, et al. Integrin-FAK signaling rapidly and potently promotes mitochondrial function through STAT3. Cell Commun Signal. 2016;14:32 pubmed
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Gutierrez E, Richardson D, Jansson P. The anticancer agent di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT) overcomes prosurvival autophagy by two mechanisms: persistent induction of autophagosome synthesis and impairment of lysosomal integrity. J Biol Chem. 2014;289:33568-89 pubmed publisher
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Vecsey C, Hawk J, Lattal K, Stein J, Fabian S, Attner M, et al. Histone deacetylase inhibitors enhance memory and synaptic plasticity via CREB:CBP-dependent transcriptional activation. J Neurosci. 2007;27:6128-40 pubmed
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Chan J, Cheng H, Chou J, Li F, Dai K, Chan S, et al. Heat shock protein 60 or 70 activates nitric-oxide synthase (NOS) I- and inhibits NOS II-associated signaling and depresses the mitochondrial apoptotic cascade during brain stem death. J Biol Chem. 2007;282:4585-600 pubmed
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product information
master code :
1229
SKU :
1229/10
product name :
Actinomycin D
unit size :
10 mg
description :
Inhibits RNA polymerase
target :
RNA/DNA Polymerase Inhibitors
category :
Small Molecules
purity :
95%
observed molecular weight :
1255.43
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Actinomycin D is an anti-neoplastic antibiotic. Inhibits RNA polymerase and is a potent inducer of apoptosis.
top caption :
Inhibits RNA polymerase
extended description :
Inhibits RNA polymerase
chemical name text :
2-Amino-(N,N)-1-bis(hexadecahydro-6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxo-1H-pyrrolo[2,1]-[1,4,7,10,13] oxatetraazacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide
formula :
C62H86N12O16
formula text :
C62H86N12O16
cas num :
50-76-0
USD :
212 USD
product details :
Inhibits RNA polymerase
storage :
Store at -20░C
more info or order :
company information

Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com800-343-7475
headquarters: UK
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