1228/10 | Tocris Bioscience 1228/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

1228/10

catalog :

1228/10

quantity :

10 mg

price :

141 USD

more info or order :

Tocris Bioscience product webpage

citations: 14

Reference
Bernier L, Bohlen C, York E, Choi H, Kamyabi A, Dissing Olesen L, et al. Nanoscale Surveillance of the Brain by Microglia via cAMP-Regulated Filopodia. Cell Rep. 2019;27:2895-2908.e4 pubmed publisher
Paonessa F, Evans L, Solanki R, Larrieu D, Wray S, Hardy J, et al. Microtubules Deform the Nuclear Membrane and Disrupt Nucleocytoplasmic Transport in Tau-Mediated Frontotemporal Dementia. Cell Rep. 2019;26:582-593.e5 pubmed publisher
Romero M, McCathie G, Jankun P, Roehl H. Damage-induced reactive oxygen species enable zebrafish tail regeneration by repositioning of Hedgehog expressing cells. Nat Commun. 2018;9:4010 pubmed publisher
Macheret M, Halazonetis T. Intragenic origins due to short G1 phases underlie oncogene-induced DNA replication stress. Nature. 2018;555:112-116 pubmed publisher
Guillaud L, Dimitrov D, Takahashi T. Presynaptic morphology and vesicular composition determine vesicle dynamics in mouse central synapses. elife. 2017;6: pubmed publisher
Guo X, Wang X, Wang Z, Banerjee S, Yang J, Huang L, et al. Site-specific proteasome phosphorylation controls cell proliferation and tumorigenesis. Nat Cell Biol. 2016;18:202-12 pubmed publisher
Tauchman E, Boehm F, DeLuca J. Stable kinetochore-microtubule attachment is sufficient to silence the spindle assembly checkpoint in human cells. Nat Commun. 2015;6:10036 pubmed publisher
Lin Y, Bhuwania R, Gromova K, Failla A, Lange T, Riecken K, et al. Drosophila homologue of Diaphanous 1 (DIAPH1) controls the metastatic potential of colon cancer cells by regulating microtubule-dependent adhesion. Oncotarget. 2015;6:18577-89 pubmed
Hutchins B, Wray S. Capture of microtubule plus-ends at the actin cortex promotes axophilic neuronal migration by enhancing microtubule tension in the leading process. Front Cell Neurosci. 2014;8:400 pubmed publisher
Melemedjian O, Tillu D, Moy J, Asiedu M, Mandell E, Ghosh S, et al. Local translation and retrograde axonal transport of CREB regulates IL-6-induced nociceptive plasticity. Mol Pain. 2014;10:45 pubmed publisher
Seese R, Babayan A, Katz A, Cox C, Lauterborn J, Lynch G, et al. LTP induction translocates cortactin at distant synapses in wild-type but not Fmr1 knock-out mice. J Neurosci. 2012;32:7403-13 pubmed publisher
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher
Rood J, Leung A, Chang P. Methods for purification of proteins associated with cellular poly(ADP-ribose) and PARP-specific poly(ADP-ribose). Methods Mol Biol. 2011;780:153-64 pubmed publisher
Schapitz I, Behrend B, Pechmann Y, Lappe Siefke C, Kneussel S, Wallace K, et al. Neuroligin 1 is dynamically exchanged at postsynaptic sites. J Neurosci. 2010;30:12733-44 pubmed publisher

product information

master code :

1228

SKU :

1228/10

product name :

Nocodazole

unit size :

10 mg

description :

Microtubule inhibitor

target :

Microtubule Binding Compounds

category :

Small Molecules

purity :

95%

observed molecular weight :

301.32

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Nocodazole is a microtubule inhibitor; inhibits mitosis. Also inhibits autophagosome-lysosome fusion. Enhances homology-directed repair (HDR) efficiency 9 to 31% (depending on cell cycle phase) and increases Cas9-mediated gene editing frequencies.

top caption :

Microtubule inhibitor

extended description :

Microtubule inhibitor

chemical name text :

[5-(2-Thienylcarbonyl)-1H-benzimidazol-2-yl]carbonic acid, methyl ester

formula :

C14H11N3O3S

formula text :

C14H11N3O3S

cas num :

31430-18-9

USD :

141 USD

product details :

Microtubule inhibitor

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage