product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
1226/100
catalog :
1226/100
quantity :
100 mg
price :
197 USD
more info or order :
citations: 5
Reference
Long Q, Li L, Wang H, Li M, Wang L, Zhou M, et al. Novel peptide dermaseptin-PS1 exhibits anticancer activity via induction of intrinsic apoptosis signalling. J Cell Mol Med. 2019;23:1300-1312 pubmed publisher
Maswadeh H, Aljarbou A, Alorainy M, Alsharidah M, Khan M. Etoposide incorporated into camel milk phospholipids liposomes shows increased activity against fibrosarcoma in a mouse model. Biomed Res Int. 2015;2015:743051 pubmed publisher
Nicolson S, Samulski R. Recombinant adeno-associated virus utilizes host cell nuclear import machinery to enter the nucleus. J Virol. 2014;88:4132-44 pubmed publisher
Li C, Wei J, Li Y, He X, Zhou Q, Yan J, et al. Transmembrane Protein 214 (TMEM214) mediates endoplasmic reticulum stress-induced caspase 4 enzyme activation and apoptosis. J Biol Chem. 2013;288:17908-17 pubmed publisher
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher
product information
master code :
1226
SKU :
1226/100
product name :
Etoposide
unit size :
100 mg
description :
Topoisomerase II inhibitor
target :
DNA Topoisomerase Inhibitors
category :
Small Molecules
purity :
99%
observed molecular weight :
588.56
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Etoposide is a DNA topoisomerase II inhibitor (IC50 = 59.2 M). Anticancer. Also enhances adeno-associated virus (AAV) transduction of HeLa cells.
top caption :
Topoisomerase II inhibitor
extended description :
Topoisomerase II inhibitor
chemical name text :
[5R-[5 ,5a ,8a ,9 (R*)]]-9-[(4,6- -Ethylidene- -D-glucopyranosyl)oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)furo[3 ,4 :6,7]naphtho[2,3-d]-1,3-dioxol-6-(5aH)-one
formula :
C29H32O13
formula text :
C29H32O13
cas num :
33419-42-0
USD :
197 USD
product details :
Topoisomerase II inhibitor
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK