DMPQ dihydrochloride | Tocris Bioscience 1222/10 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

DMPQ dihydrochloride

catalog :

1222/10

quantity :

10 mg (also 50 mg)

price :

188 USD

citations: 1

Reference
Srinivasan A, Chang S, Zhang S, Toh W, Toh Y. Substrate stiffness modulates the multipotency of human neural crest derived ectomesenchymal stem cells via CD44 mediated PDGFR signaling. Biomaterials. 2018;167:153-167 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

1222

SKU :

1222/10

product name :

DMPQ dihydrochloride

description :

Potent, selective inhibitor of PDGFR

target :

PDGF Receptor Inhibitors

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

99%

storage :

Store at RT

observed molecular weight :

339.22

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

DMPQ dihydrochloride is a potent and selective inhibitor of human vascular -type platelet derived growth factor receptor tyrosine kinase (PDGFR ) (IC50 = 80 nM). Displays 100-fold selectivity over EGFR tyrosine kinase, erbB2, p56, protein kinase A and protein kinase C.

product keywords :

Potent selective inhibitors inhibits PDGFR PDGFRbeta PDGFRb Platelet Derived Growth Factors Receptors Receptor Tyrosine Kinases RTKs PDGFR 1222,

extended description :

Potent, selective inhibitor of PDGFR

chemical name text :

5,7-Dimethoxy-3-(4-pyridinyl)quinoline dihydrochloride

formula :

C16H14N2O2.2HCl

formula text :

C16H14N2O2.2HCl

cas num :

1123491-15-5

USD :

186

USD 2025 :

188 USD

product details :

Potent, selective inhibitor of PDGFR