1218/10 | Tocris Bioscience 1218/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

1218/10

catalog :

1218/10

quantity :

10 mg (also 50 mg)

price :

194 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher
Kojima S, Tohei A, Ikeda M. Melatonin inhibits tachykinin NK? receptor-triggered 5-HT release from guinea pig isolated colonic mucosa. Br J Pharmacol. 2011;162:1179-85 pubmed publisher
Sjöblom M, Säfsten B, Flemström G. Melatonin-induced calcium signaling in clusters of human and rat duodenal enterocytes. Am J Physiol Gastrointest Liver Physiol. 2003;284:G1034-44 pubmed

image

image 1 :

Cat.No. 1218 - DH 97 C22H26N2O CAS No. 220339-00-4

product information

master code :

1218

SKU :

1218/10

product name :

DH 97

unit size :

10 mg (also 50 mg)

description :

MT2 receptor antagonist

target :

Melatonin (MT) Receptor Antagonists

category :

Small Molecules

observed molecular weight :

334.46

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

DH 97 is a relatively potent MT2 melatonin receptor antagonist (pKi value = 8.03), displaying 89- and 229-fold selectivity over MT1 and GPR50 (melatonin-related orphan receptor) respectively.

top caption :

MT2 receptor antagonist

extended description :

MT2 receptor antagonist

chemical name text :

N-Pentanoyl-2-benzyltryptamine

formula :

C22H26N2O

formula text :

C22H26N2O

cas num :

220339-00-4

USD :

194 USD

product details :

MT2 receptor antagonist

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage