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company name :
Tocris Bioscience
product type :
chemical
product name :
1213/1
catalog :
1213/1
quantity :
1 mg (also 10 mg, 50 mg)
price :
100 USD
more info or order :
citations: 109
Reference
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product information
master code :
1213
SKU :
1213/1
product name :
PD 98059
unit size :
1 mg (also 10 mg, 50 mg)
description :
MEK inhibitor
target :
MEK Inhibitors
category :
Small Molecules
purity :
98%
observed molecular weight :
267.28
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
PD 98059 is an inhibitor of mitogen-activated protein kinase kinase (MKK/ MEK). Acts by binding to the inactivated form of MEK, thereby preventing its phosphorylation by cRAF or MEK kinase (IC50 = 2-7 u M). Inhibits cell growth and proliferation in acute myelogenous leukemia (AML) cell lines; causes G1 arrest by blocking p53-dependent p21 induction. Enhances embryonic stem cell self-renewal.
top caption :
MEK inhibitor
extended description :
MEK inhibitor
chemical name text :
2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one
formula :
C16H13NO3
formula text :
C16H13NO3
cas num :
167869-21-8
USD :
100 USD
product details :
MEK inhibitor
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK