ZD 7155 hydrochloride | Tocris Bioscience 1211/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ZD 7155 hydrochloride

catalog :

1211/10

quantity :

10 mg (also 50 mg)

price :

210 USD

citations: 3

Reference
Nostramo R, Tillinger A, Saavedra J, Kumar A, Pandey V, Serova L, et al. Regulation of angiotensin II type 2 receptor gene expression in the adrenal medulla by acute and repeated immobilization stress. J Endocrinol. 2012;215:291-301 pubmed publisher
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher
Leite Moreira A, Castro Chaves P, Pimentel Nunes P, Lima Carneiro A, Guerra M, Soares J, et al. Angiotensin II acutely decreases myocardial stiffness: a novel AT1, PKC and Na+/H+ exchanger-mediated effect. Br J Pharmacol. 2006;147:690-7 pubmed

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

1211

SKU :

1211/10

product name :

ZD 7155 hydrochloride

description :

Selective non-peptide AT1 antagonist

target :

Angiotensin AT1 Receptor Antagonists

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Desiccate at +4°C

observed molecular weight :

474.99

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

ZD 7155 hydrochloride is a potent and selective competitive antagonist for the angiotensin II type 1 (AT1) receptor. Displaces [125I]-angiotensin II binding with an IC50 value of 3.8 nM in guinea pig adrenal gland membranes. Orally active, and is more potent and longer-acting than the prototype AT1 antagonist, losartan.

product keywords :

Selective non-peptide AT1 antagonists Receptors Angiotensin1 ZD7155 hydrochloride AstraZeneca Angiotensin AT1 Receptors 1211,

extended description :

Selective non-peptide AT1 antagonist

chemical name text :

5,7-Diethyl-3,4-dihydro-1-[[2 -(1H-tetrazol-5-yl)[1,1 -biphenyl]-4-yl]methyl]-1,6-naphthyridin-2(1H)-one hydrochloride

formula :

C26H26N6O.HCl

formula text :

C26H26N6O.HCl

cas num :

146709-78-6

USD :

233

USD 2025 :

210 USD

product details :

Selective non-peptide AT1 antagonist