product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
1156/5
catalog :
1156/5
quantity :
5 mg
price :
216 USD
more info or order :
citations: 17
Reference
Gutierrez S, Boada M. Neuropeptide-induced modulation of carcinogenesis in a metastatic breast cancer cell line (MDA-MB-231LUC+). Cancer Cell Int. 2018;18:216 pubmed publisher
Torres Fuentes C, Pastor Cavada E, Cano R, Kandil D, Shanahan R, Juan R, et al. Quinolones Modulate Ghrelin Receptor Signaling: Potential for a Novel Small Molecule Scaffold in the Treatment of Cachexia. Int J Mol Sci. 2018;19: pubmed publisher
Kowtharapu B, Murin R, Jünemann A, Stachs O. Role of Corneal Stromal Cells on Epithelial Cell Function during Wound Healing. Int J Mol Sci. 2018;19: pubmed publisher
Nogueras Ortiz C, Roman Vendrell C, Mateo Semidey G, Liao Y, Kendall D, Yudowski G. Retromer stops beta-arrestin 1-mediated signaling from internalized cannabinoid 2 receptors. Mol Biol Cell. 2017;28:3554-3561 pubmed publisher
Frara N, Fisher P, Zhao Y, Tarr J, Amin M, Popoff S, et al. Substance P increases CCN2 dependent on TGF-beta yet Collagen Type I via TGF-beta1 dependent and independent pathways in tenocytes. Connect Tissue Res. 2018;59:30-44 pubmed publisher
Wan F, Bai Y, Kou Z, Zhang T, Li H, Wang Y, et al. Endomorphin-2 Inhibition of Substance P Signaling within Lamina I of the Spinal Cord Is Impaired in Diabetic Neuropathic Pain Rats. Front Mol Neurosci. 2016;9:167 pubmed publisher
Fisher P, Zhao Y, Rico M, Massicotte V, WADE C, Litvin J, et al. Increased CCN2, substance P and tissue fibrosis are associated with sensorimotor declines in a rat model of repetitive overuse injury. J Cell Commun Signal. 2015;9:37-54 pubmed publisher
Chen W, McRoberts J, Marvizón J. ?-Opioid receptor inhibition of substance P release from primary afferents disappears in neuropathic pain but not inflammatory pain. Neuroscience. 2014;267:67-82 pubmed publisher
Hur S, Park J. Long-term potentiation of excitatory synaptic strength in spinothalamic tract neurons of the rat spinal cord. Korean J Physiol Pharmacol. 2013;17:553-8 pubmed publisher
Alsaqati M, Chan S, Ralevic V. Investigation of the functional expression of purine and pyrimidine receptors in porcine isolated pancreatic arteries. Purinergic Signal. 2014;10:241-9 pubmed publisher
Grant J. Tachykinins stimulate a subset of mouse taste cells. PLoS ONE. 2012;7:e31697 pubmed publisher
Robery S, Mukanowa J, Percie du Sert N, Andrews P, Williams R. Investigating the effect of emetic compounds on chemotaxis in Dictyostelium identifies a non-sentient model for bitter and hot tastant research. PLoS ONE. 2011;6:e24439 pubmed publisher
Shanley L, Lear M, Davidson S, Ross R, Mackenzie A. Evidence for regulatory diversity and auto-regulation at the TAC1 locus in sensory neurones. J Neuroinflammation. 2011;8:10 pubmed publisher
Li Y, Xi D, Roman J, Huang Y, Gao W. Activation of glycogen synthase kinase-3 beta is required for hyperdopamine and D2 receptor-mediated inhibition of synaptic NMDA receptor function in the rat prefrontal cortex. J Neurosci. 2009;29:15551-63 pubmed publisher
Hanson B, Wetter J, Bercher M, Kopp L, Fuerstenau Sharp M, Vedvik K, et al. A homogeneous fluorescent live-cell assay for measuring 7-transmembrane receptor activity and agonist functional selectivity through beta-arrestin recruitment. J Biomol Screen. 2009;14:798-810 pubmed publisher
Wease K, Davies S. Substance P selectively decreases paired pulse depression in the rat hippocampal slice. BMC Neurosci. 2005;6:66 pubmed
Howe H, Somponpun S, Sladek C. Role of neurokinin 3 receptors in supraoptic vasopressin and oxytocin neurons. J Neurosci. 2004;24:10103-10 pubmed
product information
master code :
1156
SKU :
1156/5
product name :
Substance P
unit size :
5 mg
description :
Sensory neuropeptide; inflammatory mediator
target :
Tachykinin Agonists
category :
Peptides
purity :
95%
observed molecular weight :
1347.6
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=peptides
details of functionality :
Substance P is a sensory neuropeptide and inflammatory mediator. Exerts excitatory effects on central and peripheral neurons, constricts bronchioles and is involved in pain transmission.
top caption :
Sensory neuropeptide; inflammatory mediator
extended description :
Sensory neuropeptide; inflammatory mediator
formula :
C63H98N18O13S
formula text :
C63H98N18O13S
cas num :
33507-63-0
USD :
216 USD
product details :
Sensory neuropeptide; inflammatory mediator
storage :
Store at -20░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK