product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
CRF (human, rat)
catalog :
1151
quantity :
200 ug
price :
182 USD
more info or order :
citations: 10
Reference
Xie Z, Penzes P, Srivastava D. Exchange protein directly activated by cAMP 2 is required for corticotropin-releasing hormone-mediated spine loss. Eur J Neurosci. 2019;50:3108-3114 pubmed publisher
Raftogianni A, Roth L, García González D, Bus T, Kühne C, Monyer H, et al. Deciphering the Contributions of CRH Receptors in the Brain and Pituitary to Stress-Induced Inhibition of the Reproductive Axis. Front Mol Neurosci. 2018;11:305 pubmed publisher
Song T, Bi Y, Gao Y, Huang R, Hao K, Xu G, et al. Systemic pro-inflammatory response facilitates the development of cerebral edema during short hypoxia. J Neuroinflammation. 2016;13:63 pubmed publisher
Klampfl S, Brunton P, Bayerl D, Bosch O. CRF-R1 activation in the anterior-dorsal BNST induces maternal neglect in lactating rats via an HPA axis-independent central mechanism. Psychoneuroendocrinology. 2016;64:89-98 pubmed publisher
Navarro G, Quiroz C, Moreno Delgado D, Sierakowiak A, McDowell K, Moreno E, et al. Orexin-corticotropin-releasing factor receptor heteromers in the ventral tegmental area as targets for cocaine. J Neurosci. 2015;35:6639-53 pubmed publisher
Gray J, Vecchiarelli H, Morena M, Lee T, Hermanson D, Kim A, et al. Corticotropin-releasing hormone drives anandamide hydrolysis in the amygdala to promote anxiety. J Neurosci. 2015;35:3879-92 pubmed publisher
Silberman Y, Winder D. Corticotropin releasing factor and catecholamines enhance glutamatergic neurotransmission in the lateral subdivision of the central amygdala. Neuropharmacology. 2013;70:316-23 pubmed publisher
Lowery Gionta E, Navarro M, Li C, Pleil K, Rinker J, Cox B, et al. Corticotropin releasing factor signaling in the central amygdala is recruited during binge-like ethanol consumption in C57BL/6J mice. J Neurosci. 2012;32:3405-13 pubmed publisher
Land B, Bruchas M, Lemos J, Xu M, Melief E, Chavkin C. The dysphoric component of stress is encoded by activation of the dynorphin kappa-opioid system. J Neurosci. 2008;28:407-14 pubmed publisher
Dermitzaki E, Tsatsanis C, Minas V, Chatzaki E, Charalampopoulos I, Venihaki M, et al. Corticotropin-releasing factor (CRF) and the urocortins differentially regulate catecholamine secretion in human and rat adrenals, in a CRF receptor type-specific manner. Endocrinology. 2007;148:1524-38 pubmed
product information
brand :
Tocris
master code :
1151
SKU :
1151/200U
product name :
CRF (human, rat)
description :
Stimulates ACTH release
target :
Non-selective CRF Receptor Agonists
category :
Peptides
unit size :
200 ug
species :
Human, Rat
observed molecular weight :
4758
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=peptides
details of functionality :
Endogenous peptide agonist for the CRF receptor (Ki values are 11, 44 and 38 nM for hCRF1, rCRF2a and mCRF2b respectively). Stimulates the synthesis and release of ACTH from the anterior pituitary.
catalog number base :
1151
product keywords :
Stimulates ACTH release Corticotropin-Releasing Factor Non-Selective CRF Receptors agonists Corticotropin-Releasing Factor (human, rat) Non-selective CRF 1151,
extended description :
Stimulates ACTH release
formula :
C 208 H 344 N 60 O 63 S 2
formula text :
C208H344N60O63S2
cas num :
86784-80-7
2020 USD :
178
2021 USD :
182 USD
alt names :
Corticotropin-Releasing Factor (human, rat)
storage :
Desiccate at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK