MDL 28170 | Tocris Bioscience 1146/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

MDL 28170

catalog :

1146/10

quantity :

10 mg

price :

92 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Zechel S, Nakagawa Y, Ibanez C. Thalamo-cortical axons regulate the radial dispersion of neocortical GABAergic interneurons. elife. 2016;5: pubmed publisher
Bill A, Gutierrez A, Kulkarni S, Kemp C, Bonenfant D, Voshol H, et al. ANO1/TMEM16A interacts with EGFR and correlates with sensitivity to EGFR-targeting therapy in head and neck cancer. Oncotarget. 2015;6:9173-88 pubmed
Schubert M, Panja D, Haugen M, Bramham C, Vedeler C. Paraneoplastic CDR2 and CDR2L antibodies affect Purkinje cell calcium homeostasis. Acta Neuropathol. 2014;128:835-52 pubmed publisher

product information

brand :

Tocris

SKU :

1146/10

product name :

MDL 28170

unit sizes :

10 mg

description :

Potent, selective calpain and cathepsin B inhibitor

target :

Calcium-Sensitive Protease Modulator Inhibitors

category :

Small Molecules

purity :

95%

observed molecular weight :

382.45

details of functionality :

Potent, selective inhibitor of calpain and cathepsin B (Ki values are 10 and 25 nM respectively) that does not inhibit trypsin-like serine proteases. Rapidly penetrates the blood-brain barrier following systemic administration and displays neuroprotective effects in vivo .

catalog number base :

1146

extended description :

Potent, selective calpain and cathepsin B inhibitor

chemical name text :

N-[N-[(Phenylmethoxy)carbonyl]-L-valyl]-phenylalaninal

formula :

C 22 H 26 N 2 O 4

formula text :

C22H26N2O4

cas num :

88191-84-8

USD :

92 USD

product details :

Potent, selective calpain and cathepsin B inhibitor

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage