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company name :
Tocris Bioscience
product type :
chemical
product name :
1138/1
catalog :
1138/1
quantity :
1 mg
price :
136 USD
more info or order :
citations: 48
Reference
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product information
master code :
1138
SKU :
1138/1
product name :
Thapsigargin
unit size :
1 mg
description :
Potent inhibitor of SERCA ATPase
target :
Ca2+-ATPase Inhibitors
category :
Small Molecules
purity :
97%
observed molecular weight :
650.76
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Thapsigargin is a potent inhibitor of sarco/endoplasmic reticulum Ca2+-ATPases (SERCA) that causes endoplasmic reticulum (ER) stress. Thapsigargin can be used to induce autophagy in mammalian cells. In vitro , thapsigargin blocks infection of immortilized and primary human cells with respiratory syncytial virus (RSV), SARS-CoV-2 and influenza A. Thapsigargin protects mice against lethal influenza A viral infection and reduces virus titres in the lungs of treated mice.
top caption :
Potent inhibitor of SERCA ATPase
extended description :
Potent inhibitor of SERCA ATPase
chemical name text :
(3S,3aR,4S,6S,6AR,7S,8S,9bS)-6-(Acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[[(2Z)-2-methyl-1-oxo-2-butenyl]oxy]-2-oxo-4-(1-oxobutoxy)azuleno[4,5-b]furan-7-yl octanoate
formula :
C34H50O12
formula text :
C34H50O12
cas num :
67526-95-8
USD :
136 USD
product details :
Potent inhibitor of SERCA ATPase
storage :
Store at -20░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK