product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Quercetin
catalog :
1125
quantity :
100 mg
price :
75 USD
more info or order :
citations: 3
Reference
Yao X, Su T, Verkman A. Clobetasol promotes remyelination in a mouse model of neuromyelitis optica. Acta Neuropathol Commun. 2016;4:42 pubmed publisher
Rees M, Seashore Ludlow B, Cheah J, Adams D, Price E, Gill S, et al. Correlating chemical sensitivity and basal gene expression reveals mechanism of action. Nat Chem Biol. 2016;12:109-16 pubmed publisher
Filone C, Caballero I, Dower K, Mendillo M, Cowley G, Santagata S, et al. The master regulator of the cellular stress response (HSF1) is critical for orthopoxvirus infection. PLoS Pathog. 2014;10:e1003904 pubmed publisher
product information
brand :
Tocris
master code :
1125
SKU :
1125/100
product name :
Quercetin
description :
Non-selective PI 3-kinase inhibitor
target :
Inositol Lipid Inhibitors
category :
Small Molecules
unit size :
100 mg
purity :
98%
observed molecular weight :
302.24
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Antitumor agent; induces apoptosis and inhibits synthesis of heat shock proteins. Inhibits many enzyme systems including tyrosine protein kinase, phospholipase A2, phosphodiesterases, mitochondrial ATPase, PI 3-kinase and protein kinase C. Can also activate Ca2+ and K+ channels and behaves as an agonist at estrogen (GPER) receptors. Blocks cellular entry by influenza A virus via an interaction with hemaglutinin. Inhibits SARS-CoV 3CLpro (IC50 = 73 M).
catalog number base :
1125
product keywords :
Non-Selective PI 3-kinase inhibitors inhibits GPR30 agonists non-selective 3-Kinase PI3K Akt Signaling Signalling PIP2 Inositol Lipids cAMP Receptors Estrogen receptors Phosphoinositide Kinases GPER antiviral influenza virus SARS-Cov coronavirus 3CLpro Inositol Lipids PI 3-Kinase Estrogen (GPER) Receptors IRE1 COVID-19 3C and 3CL Proteases Influenza Viruses Coronavirus 1125,
extended description :
Non-selective PI 3-kinase inhibitor
chemical name text :
2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one
formula :
C 15 H 10 O 7
formula text :
C15H10O7
cas num :
117-39-5
2020 USD :
72
2021 USD :
75 USD
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK