1125/100 | Tocris Bioscience 1125/100 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

1125/100

catalog :

1125/100

quantity :

100 mg

price :

99 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Yao X, Su T, Verkman A. Clobetasol promotes remyelination in a mouse model of neuromyelitis optica. Acta Neuropathol Commun. 2016;4:42 pubmed publisher
Rees M, Seashore Ludlow B, Cheah J, Adams D, Price E, Gill S, et al. Correlating chemical sensitivity and basal gene expression reveals mechanism of action. Nat Chem Biol. 2016;12:109-16 pubmed publisher
Filone C, Caballero I, Dower K, Mendillo M, Cowley G, Santagata S, et al. The master regulator of the cellular stress response (HSF1) is critical for orthopoxvirus infection. PLoS Pathog. 2014;10:e1003904 pubmed publisher
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher

product information

master code :

1125

SKU :

1125/100

product name :

Quercetin

unit size :

100 mg

description :

Non-selective PI 3-kinase inhibitor

target :

Inositol Lipid Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

302.24

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Quercetin is an antitumor agent; induces apoptosis and inhibits synthesis of heat shock proteins. Inhibits many enzyme systems including tyrosine protein kinase, phospholipase A2, phosphodiesterases, mitochondrial ATPase, PI 3-kinase and protein kinase C. Can also activate Ca2+ and K+ channels and behaves as an agonist at estrogen (GPER) receptors. Blocks cellular entry by influenza A virus via an interaction with hemaglutinin. Inhibits SARS-CoV 3CLpro (IC50 = 73 M). Targets and eliminates senescent cells. Orally bioavailable.

top caption :

Non-selective PI 3-kinase inhibitor

extended description :

Non-selective PI 3-kinase inhibitor

chemical name text :

2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one

formula :

C15H10O7

formula text :

C15H10O7

cas num :

117-39-5

USD :

99 USD

product details :

Non-selective PI 3-kinase inhibitor

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage