Ketoconazole | Tocris Bioscience 1103 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Ketoconazole

catalog :

1103

quantity :

100 mg

price :

127 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Lu C, Leong P, Hou T, Kang Y, Chiang Y, Hsu C, et al. Inhibition of proliferation and migration of melanoma cells by ketoconazole and Ganoderma immunomodulatory proteins. Oncol Lett. 2019;18:891-897 pubmed publisher
Green D, Ruparel S, Gao X, Ruparel N, Patil M, AKOPIAN A, et al. Central activation of TRPV1 and TRPA1 by novel endogenous agonists contributes to mechanical allodynia and thermal hyperalgesia after burn injury. Mol Pain. 2016;12: pubmed publisher
Green D, Ruparel S, Roman L, Henry M, Hargreaves K. Role of endogenous TRPV1 agonists in a postburn pain model of partial-thickness injury. Pain. 2013;154:2512-20 pubmed publisher
Ruparel S, Green D, Chen P, Hargreaves K. The cytochrome P450 inhibitor, ketoconazole, inhibits oxidized linoleic acid metabolite-mediated peripheral inflammatory pain. Mol Pain. 2012;8:73 pubmed publisher

product information

brand :

Tocris

master code :

1103

SKU :

1103/100

product name :

Ketoconazole

description :

Cytochrome P450c17 inhibitor

target :

Cytochrome P450 Inhibitors

category :

Small Molecules

unit size :

100 mg

purity :

99%

observed molecular weight :

531.44

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Inhibitor of cytochrome P450c17. Enhances the formation of myelin basic protein-positive oligodendrocytes from oligodendrocyte progenitor cells in vitro and promotes remyelination in vivo . Also an antifungal agent. Brain penetrant.

catalog number base :

1103

product keywords :

Cytochrome P450c17 inhibitors inhibits CYP antifingal promotes myelination oligodendrocyte differentiation Cytochrome P450 Other Differentiation Products 1103,

extended description :

Cytochrome P450c17 inhibitor

chemical name text :

cis-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl] methoxy]phenyl]piperazine

formula :

C 26 H 28 Cl 2 N 4 O 4

formula text :

C26H28Cl2N4O4

cas num :

65277-42-1

2020 USD :

123

2021 USD :

127 USD

storage :

Desiccate at +4°C

more info or order :

Tocris Bioscience product webpage