1103/100 | Tocris Bioscience 1103/100 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

1103/100

catalog :

1103/100

quantity :

100 mg

price :

160 USD

more info or order :

Tocris Bioscience product webpage

citations: 5

Reference
Lu C, Leong P, Hou T, Kang Y, Chiang Y, Hsu C, et al. Inhibition of proliferation and migration of melanoma cells by ketoconazole and Ganoderma immunomodulatory proteins. Oncol Lett. 2019;18:891-897 pubmed publisher
Green D, Ruparel S, Gao X, Ruparel N, Patil M, AKOPIAN A, et al. Central activation of TRPV1 and TRPA1 by novel endogenous agonists contributes to mechanical allodynia and thermal hyperalgesia after burn injury. Mol Pain. 2016;12: pubmed publisher
Green D, Ruparel S, Roman L, Henry M, Hargreaves K. Role of endogenous TRPV1 agonists in a postburn pain model of partial-thickness injury. Pain. 2013;154:2512-20 pubmed publisher
Ruparel S, Green D, Chen P, Hargreaves K. The cytochrome P450 inhibitor, ketoconazole, inhibits oxidized linoleic acid metabolite-mediated peripheral inflammatory pain. Mol Pain. 2012;8:73 pubmed publisher
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher

product information

master code :

1103

SKU :

1103/100

product name :

Ketoconazole

unit size :

100 mg

description :

Cytochrome P450c17 inhibitor

target :

Cytochrome P450 Inhibitors

category :

Small Molecules

purity :

99%

observed molecular weight :

531.44

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Ketoconazole is an inhibitor of cytochrome P450c17. Enhances the formation of myelin basic protein-positive oligodendrocytes from oligodendrocyte progenitor cells in vitro and promotes remyelination in vivo . Also an antifungal agent. Brain penetrant.

top caption :

Cytochrome P450c17 inhibitor

extended description :

Cytochrome P450c17 inhibitor

chemical name text :

cis-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl] methoxy]phenyl]piperazine

formula :

C26H28Cl2N4O4

formula text :

C26H28Cl2N4O4

cas num :

65277-42-1

USD :

160 USD

product details :

Cytochrome P450c17 inhibitor

storage :

Desiccate at +4░C

more info or order :

Tocris Bioscience product webpage