product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
1100/25
catalog :
1100/25
quantity :
25 mg
price :
110 USD
more info or order :
citations: 7
Reference
Herz C, Tran H, Marton M, Maul R, Baldermann S, Schreiner M, et al. Evaluation of an Aqueous Extract from Horseradish Root (Armoracia rusticana Radix) against Lipopolysaccharide-Induced Cellular Inflammation Reaction. Evid Based Complement Alternat Med. 2017;2017:1950692 pubmed publisher
Neveu B, Spinella J, Richer C, Lagacé K, Cassart P, Lajoie M, et al. CLIC5: a novel ETV6 target gene in childhood acute lymphoblastic leukemia. Haematologica. 2016;101:1534-1543 pubmed
Hellinger R, Koehbach J, Fedchuk H, Sauer B, Huber R, Gruber C, et al. Immunosuppressive activity of an aqueous Viola tricolor herbal extract. J Ethnopharmacol. 2014;151:299-306 pubmed publisher
Lamy E, Hertrampf A, Herz C, Schuler J, Erlacher M, Bertele D, et al. Preclinical evaluation of 4-methylthiobutyl isothiocyanate on liver cancer and cancer stem cells with different p53 status. PLoS ONE. 2013;8:e70846 pubmed publisher
Gründemann C, Thell K, Lengen K, Garcia Käufer M, Huang Y, Huber R, et al. Cyclotides Suppress Human T-Lymphocyte Proliferation by an Interleukin 2-Dependent Mechanism. PLoS ONE. 2013;8:e68016 pubmed publisher
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher
Ma M, Qian H, Ghassemi F, Zhao P, Xia Y. Oxygen-sensitive {delta}-opioid receptor-regulated survival and death signals: novel insights into neuronal preconditioning and protection. J Biol Chem. 2005;280:16208-18 pubmed
product information
master code :
1100
SKU :
1100/25
product name :
Camptothecin
unit size :
25 mg
description :
DNA topoisomerase inhibitor
target :
DNA Topoisomerase Inhibitors
category :
Small Molecules
purity :
98%
observed molecular weight :
348.36
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Camptothecin is a cytotoxic plant alkaloid with antitumor properties; prototypic DNA topoisomerase I inhibitor. Induces single strand DNA breaks and protein-DNA crosslinks.
top caption :
DNA topoisomerase inhibitor
extended description :
DNA topoisomerase inhibitor
chemical name text :
(S)-4-Ethyl-4-hydroxy-1H-pyrano-[3 ,4 :6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
formula :
C20H16N2O4
formula text :
C20H16N2O4
cas num :
3/4/89
USD :
110 USD
product details :
DNA topoisomerase inhibitor
storage :
Store at +4░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK