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company name :
Tocris Bioscience
product type :
chemical
product name :
Forskolin
catalog :
1099
quantity :
10 mg (also 50 mg)
price :
163 USD
more info or order :
citations: 85
Reference
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Yang J, Polanowska Grabowska R, Smith J, Shields C, Saucerman J. PKA catalytic subunit compartmentation regulates contractile and hypertrophic responses to ?-adrenergic signaling. J Mol Cell Cardiol. 2014;66:83-93 pubmed publisher
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Ehrlich A, Furuyashiki T, Kitaoka S, Kakizuka A, Narumiya S. Prostaglandin E receptor EP1 forms a complex with dopamine D1 receptor and directs D1-induced cAMP production to adenylyl cyclase 7 through mobilizing G(??) subunits in human embryonic kidney 293T cells. Mol Pharmacol. 2013;84:476-86 pubmed publisher
Wiseman S, Shimizu Y, Palfrey C, Nairn A. Proteasomal degradation of eukaryotic elongation factor-2 kinase (EF2K) is regulated by cAMP-PKA signaling and the SCF?TRCP ubiquitin E3 ligase. J Biol Chem. 2013;288:17803-11 pubmed publisher
Pale T, Frisch E, McClellan A. Cyclic AMP stimulates neurite outgrowth of lamprey reticulospinal neurons without substantially altering their biophysical properties. Neuroscience. 2013;245:74-89 pubmed publisher
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Kaufman A, Milnerwood A, Sepers M, Coquinco A, She K, Wang L, et al. Opposing roles of synaptic and extrasynaptic NMDA receptor signaling in cocultured striatal and cortical neurons. J Neurosci. 2012;32:3992-4003 pubmed publisher
Van Hook M, Wong K, Berson D. Dopaminergic modulation of ganglion-cell photoreceptors in rat. Eur J Neurosci. 2012;35:507-18 pubmed publisher
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Chen Y, Yue S, Xie L, Pu X, Jin T, Cheng S. Dual Phosphorylation of suppressor of fused (Sufu) by PKA and GSK3beta regulates its stability and localization in the primary cilium. J Biol Chem. 2011;286:13502-11 pubmed publisher
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Althaus M, Pichl A, Clauss W, Seeger W, Fronius M, Morty R. Nitric oxide inhibits highly selective sodium channels and the Na+/K+-ATPase in H441 cells. Am J Respir Cell Mol Biol. 2011;44:53-65 pubmed publisher
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product information
brand :
Tocris
master code :
1099
SKU :
1099/10
product name :
Forskolin
description :
Adenylyl cyclase activator
target :
Adenylyl Cyclase Activators
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
98%
observed molecular weight :
410.51
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Cell-permeable activator of adenylyl cyclase. Hypotensive and vasodilatory agent. Induces neuronal differentiation in stem cells and in several neuroblastoma. Used to reprogram mouse embryonic fibroblasts to induced pluripotent stem cells in combination with three other small molecules (Cat. Nos. 3742, 4423 and 4703 ). . Negative Control also available.
catalog number base :
1099
product keywords :
Adenylyl cyclases activator Inositol cAMP Signaling Signalling adenylate stem cells organoids Adenylyl Cyclase Enzyme Substrates/ Activators Neural Stem Cells Organoids 1099,
extended description :
Adenylyl cyclase activator
chemical name text :
(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(Acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho[2,1-b]pyran-1-one
formula :
C 22 H 34 O 7
formula text :
C22H34O7
cas num :
66575-29-9
2020 USD :
155
2021 USD :
163 USD
storage :
Store at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK