product summary
Loading...
company name :
Tocris Bioscience
product type :
chemical
product name :
1098/10
catalog :
1098/10
quantity :
10 mg (also 50 mg)
price :
188 USD
more info or order :
citations: 1
Reference
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher
image
image 1 :
Tocris Bioscience 1098/10 image 1
Cat.No. 1098 - Tranilast C18H17NO5 CAS No. 53902-12-8
product information
master code :
1098
SKU :
1098/10
product name :
Tranilast
unit size :
10 mg (also 50 mg)
description :
Antiallergic; inhibits inflammatory mediator release from mast cells
target :
Miscellaneous Compounds
category :
Small Molecules
purity :
99%
observed molecular weight :
327.34
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Tranilast is an antiallergic via inhibition of chemical mediator release from mast cells. Shown to be an effective inhibitor of angiogenesis. Demonstrated to antagonize the effects of angiotensin II on human arteries, possibly by an interaction at the level of the AT1 receptor. Inhibits TRPV2-mediated responses; binds to A 40 monomers and increases A 40 fibrillation.
top caption :
Antiallergic; inhibits inflammatory mediator release from mast cells
extended description :
Antiallergic; inhibits inflammatory mediator release from mast cells
chemical name text :
2-[[3-(3,4-Dimethoxyphenyl)-1-oxo-2-propenyl]amino]benzoic acid
formula :
C18H17NO5
formula text :
C18H17NO5
cas num :
53902-12-8
USD :
188 USD
product details :
Antiallergic; inhibits inflammatory mediator release from mast cells
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK