1093/10 | Tocris Bioscience 1093/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

1093/10

catalog :

1093/10

quantity :

10 mg (also 50 mg)

price :

146 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Griffiths K, Habiel D, Jaffar J, Binder U, Darby W, Hosking C, et al. Anti-fibrotic Effects of CXCR4-Targeting i-body AD-114 in Preclinical Models of Pulmonary Fibrosis. Sci Rep. 2018;8:3212 pubmed publisher
Habiel D, Krepostman N, Lilly M, Cavassani K, Coelho A, Shibata T, et al. Senescent stromal cell-induced divergence and therapeutic resistance in T cell acute lymphoblastic leukemia/lymphoma. Oncotarget. 2016;7:83514-83529 pubmed publisher
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher

product information

master code :

1093

SKU :

1093/10

product name :

Pirfenidone

unit size :

10 mg (also 50 mg)

description :

Antifibrotic agent; regulates cytokine levels in vivo

target :

Cytokine Compounds

category :

Small Molecules

purity :

99%

observed molecular weight :

185.23

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Pirfenidone is a antifibrotic agent, effective in models of pulmonary and lung fibrosis. Inhibits collagen production and fibroblast proliferation. Regulates cytokine levels following oral administration in vivo . Potent scavenger of free radicals and inhibitor of lipid peroxidation.

top caption :

Antifibrotic agent; regulates cytokine levels in vivo

extended description :

Antifibrotic agent; regulates cytokine levels in vivo

chemical name text :

5-methyl-1-phenyl-2(1H)-pyridinone

formula :

C12H11NO

formula text :

C12H11NO

cas num :

53179-13-8

USD :

146 USD

product details :

Antifibrotic agent; regulates cytokine levels in vivo

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage