product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
1085/250U
catalog :
1085/250U
quantity :
250 ug
price :
478 USD
more info or order :
citations: 18
Reference
Bellono N, Leitch D, Julius D. Molecular basis of ancestral vertebrate electroreception. Nature. 2017;543:391-396 pubmed publisher
Fawley J, Hofmann M, Andresen M. Distinct Calcium Sources Support Multiple Modes of Synaptic Release from Cranial Sensory Afferents. J Neurosci. 2016;36:8957-66 pubmed publisher
Cassilly C, Maddox M, Cherian P, Bowling J, Hamann M, Lee R, et al. SB-224289 Antagonizes the Antifungal Mechanism of the Marine Depsipeptide Papuamide A. PLoS ONE. 2016;11:e0154932 pubmed publisher
Perissinotti P, Ethington E, Almazan E, Martínez Hernández E, Kalil J, Koob M, et al. Calcium current homeostasis and synaptic deficits in hippocampal neurons from Kelch-like 1 knockout mice. Front Cell Neurosci. 2014;8:444 pubmed publisher
McDavid S, Bauer M, Brindley R, Jewell M, Currie K. Butanol isomers exert distinct effects on voltage-gated calcium channel currents and thus catecholamine secretion in adrenal chromaffin cells. PLoS ONE. 2014;9:e109203 pubmed publisher
Szabó G, Lenkey N, Holderith N, Andrási T, Nusser Z, Hajos N. Presynaptic calcium channel inhibition underlies CB? cannabinoid receptor-mediated suppression of GABA release. J Neurosci. 2014;34:7958-63 pubmed publisher
Pan B, Guo Y, Kwok W, Hogan Q, Wu H. Sigma-1 receptor antagonism restores injury-induced decrease of voltage-gated Ca2+ current in sensory neurons. J Pharmacol Exp Ther. 2014;350:290-300 pubmed publisher
Smith N, Hone A, Memon T, Bossi S, Smith T, McIntosh J, et al. Comparative functional expression of nAChR subtypes in rodent DRG neurons. Front Cell Neurosci. 2013;7:225 pubmed publisher
Schuwald A, Nöldner M, Wilmes T, Klugbauer N, Leuner K, Muller W. Lavender oil-potent anxiolytic properties via modulating voltage dependent calcium channels. PLoS ONE. 2013;8:e59998 pubmed publisher
Medrihan L, Cesca F, Raimondi A, Lignani G, Baldelli P, Benfenati F. Synapsin II desynchronizes neurotransmitter release at inhibitory synapses by interacting with presynaptic calcium channels. Nat Commun. 2013;4:1512 pubmed publisher
Mahler S, Hensley Simon M, Tahsili Fahadan P, Lalumiere R, Thomas C, Fallon R, et al. Modafinil attenuates reinstatement of cocaine seeking: role for cystine-glutamate exchange and metabotropic glutamate receptors. Addict Biol. 2014;19:49-60 pubmed publisher
Mire E, Mezzera C, Leyva Díaz E, Paternain A, Squarzoni P, Bluy L, et al. Spontaneous activity regulates Robo1 transcription to mediate a switch in thalamocortical axon growth. Nat Neurosci. 2012;15:1134-43 pubmed publisher
Izzo A, Capasso R, Aviello G, Borrelli F, Romano B, Piscitelli F, et al. Inhibitory effect of cannabichromene, a major non-psychotropic cannabinoid extracted from Cannabis sativa, on inflammation-induced hypermotility in mice. Br J Pharmacol. 2012;166:1444-60 pubmed publisher
Grubb M, Burrone J. Activity-dependent relocation of the axon initial segment fine-tunes neuronal excitability. Nature. 2010;465:1070-4 pubmed publisher
Kim J, Alger B. Reduction in endocannabinoid tone is a homeostatic mechanism for specific inhibitory synapses. Nat Neurosci. 2010;13:592-600 pubmed publisher
Chang C, Mennerick S. Dynamic modulation of phasic and asynchronous glutamate release in hippocampal synapses. J Neurophysiol. 2010;103:392-401 pubmed publisher
Chu J, Lee L, Lai C, Vaudry H, Chan Y, Yung W, et al. Secretin as a neurohypophysial factor regulating body water homeostasis. Proc Natl Acad Sci U S A. 2009;106:15961-6 pubmed publisher
Haeberle H, Fujiwara M, Chuang J, Medina M, Panditrao M, Bechstedt S, et al. Molecular profiling reveals synaptic release machinery in Merkel cells. Proc Natl Acad Sci U S A. 2004;101:14503-8 pubmed
image
image 1 :
Tocris Bioscience 1085/250U image 1
CaV2.2 blocker
product information
master code :
1085
SKU :
1085/250U
product name :
w-Conotoxin GVIA
unit size :
250 ug
description :
CaV2.2 blocker
target :
Cav2.x Channel Blockers
category :
Peptides
purity :
95%
observed molecular weight :
3037
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=peptides
details of functionality :
-Conotoxin GVIA is a peptide neurotoxin; selectively and reversibly blocks N-type calcium channels (IC50 = 0.15 nM). Reduces ( RS )-3,5-DHPG (Cat. No. 0342)-induced long term depression in vivo .
top caption :
CaV2.2 blocker
extended description :
CaV2.2 blocker
formula :
C120H182N38O43S6
formula text :
C120H182N38O43S6
cas num :
106375-28-4
USD :
478 USD
product details :
CaV2.2 blocker
storage :
Store at -20░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK