(R)-(+)-8-Hydroxy-DPAT hydrobromide | Tocris Bioscience 1080/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

(R)-(+)-8-Hydroxy-DPAT hydrobromide

catalog :

1080/10

quantity :

10 mg (also 50 mg)

price :

225 USD

citations: 4

Reference
Sadiq A, Menchetti I, Shah A, Jeschke M, Belo C, Carlos Alcalde W, et al. 5-HT1A Receptor Function Makes Wound Healing a Happier Process. Front Pharmacol. 2018;9:1406 pubmed publisher
Cassilly C, Maddox M, Cherian P, Bowling J, Hamann M, Lee R, et al. SB-224289 Antagonizes the Antifungal Mechanism of the Marine Depsipeptide Papuamide A. PLoS ONE. 2016;11:e0154932 pubmed publisher
Wieronska J, Sławińska A, Łasoń Tyburkiewicz M, Gruca P, Papp M, Zorn S, et al. The antipsychotic-like effects in rodents of the positive allosteric modulator Lu AF21934 involve 5-HT1A receptor signaling: mechanistic studies. Psychopharmacology (Berl). 2015;232:259-73 pubmed publisher
Rossi D, Burke T, Hensler J. Differential regulation of serotonin-1A receptor-stimulated [35S]GTP gamma S binding in the dorsal raphe nucleus by citalopram and escitalopram. Eur J Pharmacol. 2008;583:103-7 pubmed publisher

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

1080

SKU :

1080/10

product name :

(R)-(+)-8-Hydroxy-DPAT hydrobromide

Description :

Selective 5-HT1A agonist; enantiomer of 8-Hydroxy-DPAT hydrobromide (Cat. No. 0529)

target :

5-HT1 Receptor Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

328.29

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

( R )-(+)-8-Hydroxy-DPAT hydrobromide is a full 5-HT1A serotonin receptor agonist. Reduces hippocampal 5-HT levels following systemic administration in rats in vivo . More active enantiomer of 8-Hydroxy-DPAT hydrobromide . . Racemate and 7-Hydroxy Isomer also available.

extended description :

Selective 5-HT1A agonist; enantiomer of 8-Hydroxy-DPAT hydrobromide (Cat. No. 0529)

chemical name text :

(2R)-(+)-8-Hydroxy-2-(di-n-propylamino)tetralin hydrobromide

formula :

C 16 H 25 NO.HBr

formula text :

C16H25NO.HBr

cas num :

78095-19-9

USD :

225 USD

product details :

Selective 5-HT1A agonist; enantiomer of 8-Hydroxy-DPAT hydrobromide (Cat. No. 0529)

storage :

Desiccate at +4°C