product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Ouabain
catalog :
1076
quantity :
100 mg
price :
85 USD
more info or order :
citations: 9
Reference
Babola T, Kersbergen C, Wang H, Bergles D. Purinergic signaling in cochlear supporting cells reduces hair cell excitability by increasing the extracellular space. elife. 2020;9: pubmed publisher
Romanos J, Benke D, Saab A, Zeilhofer H, Santello M. Differences in glutamate uptake between cortical regions impact neuronal NMDA receptor activation. Commun Biol. 2019;2:127 pubmed publisher
Woo J, Han Y, Koh W, Won J, Park M, An H, et al. Pharmacological Dissection of Intrinsic Optical Signal Reveals a Functional Coupling between Synaptic Activity and Astrocytic Volume Transient. Exp Neurobiol. 2019;28:30-42 pubmed publisher
Zhang S, Liu D, Wang L, Li Y, Wang Y, Zhang H, et al. A CASPR1-ATP1B3 protein interaction modulates plasma membrane localization of Na+/K+-ATPase in brain microvascular endothelial cells. J Biol Chem. 2019;294:6375-6386 pubmed publisher
Yin W, Kim H, Wang S, Gunawan F, Wang L, Kishimoto K, et al. The potassium channel KCNJ13 is essential for smooth muscle cytoskeletal organization during mouse tracheal tubulogenesis. Nat Commun. 2018;9:2815 pubmed publisher
Ismael Badarneh R, Guetta J, Klorin G, Berger G, Abu Saleh N, Abassi Z, et al. The Role of Angiotensin II and Cyclic AMP in Alveolar Active Sodium Transport. PLoS ONE. 2015;10:e0134175 pubmed publisher
Pál I, Kardos J, Dobolyi Ã, Héja L. Appearance of fast astrocytic component in voltage-sensitive dye imaging of neural activity. Mol Brain. 2015;8:35 pubmed publisher
Grassin Delyle S, Abrial C, Fayad Kobeissi S, Brollo M, Faisy C, Alvarez J, et al. The expression and relaxant effect of bitter taste receptors in human bronchi. Respir Res. 2013;14:134 pubmed publisher
Genda E, Jackson J, Sheldon A, Locke S, Greco T, O Donnell J, et al. Co-compartmentalization of the astroglial glutamate transporter, GLT-1, with glycolytic enzymes and mitochondria. J Neurosci. 2011;31:18275-88 pubmed publisher
product information
brand :
Tocris
master code :
1076
SKU :
1076/100
product name :
Ouabain
description :
Na+/K+ ATPase inhibitor
target :
Na+/K+ ATPase Inhibitors
category :
Small Molecules
unit size :
100 mg
purity :
95%
observed molecular weight :
584.66
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Selective Na+, K+-ATPase inhibitor. Cardiotonic agent. Also exhibits anti-MERS-CoV activity in Vero cells in vitro (IC50 = 0.08 M).
catalog number base :
1076
product keywords :
Na+K+-ATPases inhibitors inhibits Ion Pumps Transporters COVID-19 MERS-CoV middle eastern respiratory virus coronavirus Na+/K+ ATPase COVID-19 Coronavirus 1076,
extended description :
Na+/K+ ATPase inhibitor
chemical name text :
3-[(6-Deoxy- -L-mannopyranosyl)oxy]-1,5,11 ,14,19-pentahydoxycard-20(22)-enolide
formula :
C 29 H 44 O 12
formula text :
C29H44O12
cas num :
630-60-4
2020 USD :
83
2021 USD :
85 USD
storage :
Store at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK