product summary
Loading...
company name :
Tocris Bioscience
product type :
chemical
product name :
1075/100
catalog :
1075/100
quantity :
100 mg
price :
113 USD
more info or order :
citations: 42
Reference
Lopez J, L xfc cken M, Brivio E, Karamihalev S, Kos A, De Donno C, et al. Ketamine exerts its sustained antidepressant effects via cell-type-specific regulation of Kcnq2. Neuron. 2022;110:2283-2298.e9 pubmed publisher
PHELPS C, Chess Williams R, Moro C. The Dependence of Urinary Bladder Responses on Extracellular Calcium Varies Between Muscarinic, Histamine, 5-HT (Serotonin), Neurokinin, Prostaglandin, and Angiotensin Receptor Activation. Front Physiol. 2022;13:841181 pubmed publisher
Ciappelloni S, Bouchet D, Dubourdieu N, Boué Grabot E, Kellermayer B, Manso C, et al. Aquaporin-4 Surface Trafficking Regulates Astrocytic Process Motility and Synaptic Activity in Health and Autoimmune Disease. Cell Rep. 2019;27:3860-3872.e4 pubmed publisher
Bellono N, Leitch D, Julius D. Molecular basis of ancestral vertebrate electroreception. Nature. 2017;543:391-396 pubmed publisher
Florea A, Varghese E, McCallum J, Mahgoub S, Helmy I, Varghese S, et al. Calcium-regulatory proteins as modulators of chemotherapy in human neuroblastoma. Oncotarget. 2017;8:22876-22893 pubmed publisher
Mauger O, Lemoine F, Scheiffele P. Targeted Intron Retention and Excision for Rapid Gene Regulation in Response to Neuronal Activity. Neuron. 2016;92:1266-1278 pubmed publisher
Boo H, Min H, Jang H, Yun H, Smith J, Jin Q, et al. The tobacco-specific carcinogen-operated calcium channel promotes lung tumorigenesis via IGF2 exocytosis in lung epithelial cells. Nat Commun. 2016;7:12961 pubmed publisher
Pigott B, Garthwaite J. Nitric Oxide Is Required for L-Type Ca(2+) Channel-Dependent Long-Term Potentiation in the Hippocampus. Front Synaptic Neurosci. 2016;8:17 pubmed publisher
Kraidith K, Svasti S, Teerapornpuntakit J, Vadolas J, Chaimana R, Lapmanee S, et al. Hepcidin and 1,25(OH)2D3 effectively restore Ca2+ transport in β-thalassemic mice: reciprocal phenomenon of Fe2+ and Ca2+ absorption. Am J Physiol Endocrinol Metab. 2016;311:E214-23 pubmed publisher
Hanlon K, Lozano Ondoua A, Umaretiya P, Symons Liguori A, Chandramouli A, Moy J, et al. Modulation of breast cancer cell viability by a cannabinoid receptor 2 agonist, JWH-015, is calcium dependent. Breast Cancer (Dove Med Press). 2016;8:59-71 pubmed publisher
Lee K, Royston S, Vest M, Ley D, Lee S, Bolton E, et al. N-methyl-D-aspartate receptors mediate activity-dependent down-regulation of potassium channel genes during the expression of homeostatic intrinsic plasticity. Mol Brain. 2015;8:4 pubmed publisher
Wang Y, Mattson M. L-type Ca2+ currents at CA1 synapses, but not CA3 or dentate granule neuron synapses, are increased in 3xTgAD mice in an age-dependent manner. Neurobiol Aging. 2014;35:88-95 pubmed publisher
Armstrong G, Drapeau P. Calcium channel agonists protect against neuromuscular dysfunction in a genetic model of TDP-43 mutation in ALS. J Neurosci. 2013;33:1741-52 pubmed publisher
Tung S, Hardy A, Wheeler M, Belsham D. Serotonin (5-HT) activation of immortalized hypothalamic neuronal cells through the 5-HT1B serotonin receptor. Endocrinology. 2012;153:4862-73 pubmed
Kim E, Owen B, Holmes W, Grover L. Decreased afferent excitability contributes to synaptic depression during high-frequency stimulation in hippocampal area CA1. J Neurophysiol. 2012;108:1965-76 pubmed publisher
Mire E, Mezzera C, Leyva Díaz E, Paternain A, Squarzoni P, Bluy L, et al. Spontaneous activity regulates Robo1 transcription to mediate a switch in thalamocortical axon growth. Nat Neurosci. 2012;15:1134-43 pubmed publisher
Yang C, Huang C, Hsu K. A critical role for protein tyrosine phosphatase nonreceptor type 5 in determining individual susceptibility to develop stress-related cognitive and morphological changes. J Neurosci. 2012;32:7550-62 pubmed publisher
Ring H, Mendu S, Shirazi Fard S, Birnir B, Hallböök F. GABA maintains the proliferation of progenitors in the developing chick ciliary marginal zone and non-pigmented ciliary epithelium. PLoS ONE. 2012;7:e36874 pubmed publisher
Kaufman A, Milnerwood A, Sepers M, Coquinco A, She K, Wang L, et al. Opposing roles of synaptic and extrasynaptic NMDA receptor signaling in cocultured striatal and cortical neurons. J Neurosci. 2012;32:3992-4003 pubmed publisher
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher
Caiati M, Sivakumaran S, Lanore F, Mulle C, Richard E, Verrier D, et al. Developmental regulation of CB1-mediated spike-time dependent depression at immature mossy fiber-CA3 synapses. Sci Rep. 2012;2:285 pubmed publisher
Zemkova H, Stojilkovic S, Klein D. Norepinephrine causes a biphasic change in mammalian pinealocye membrane potential: role of alpha1B-adrenoreceptors, phospholipase C, and Ca2+. Endocrinology. 2011;152:3842-51 pubmed publisher
Kim S, Rhim H. Effects of amyloid-? peptides on voltage-gated L-type Ca(V)1.2 and Ca(V)1.3 Ca(2+) channels. Mol Cells. 2011;32:289-94 pubmed publisher
Abe H, Okazawa M, Nakanishi S. The Etv1/Er81 transcription factor orchestrates activity-dependent gene regulation in the terminal maturation program of cerebellar granule cells. Proc Natl Acad Sci U S A. 2011;108:12497-502 pubmed publisher
Chen M, Wan Y, ADE K, Ting J, Feng G, Calakos N. Sapap3 deletion anomalously activates short-term endocannabinoid-mediated synaptic plasticity. J Neurosci. 2011;31:9563-73 pubmed publisher
Luoma J, Kelley B, Mermelstein P. Progesterone inhibition of voltage-gated calcium channels is a potential neuroprotective mechanism against excitotoxicity. Steroids. 2011;76:845-55 pubmed publisher
Xu K, Zhu W, Chen L, deFilippi C, Zhang J, Xiao R. Mechanistic distinction between activation and inhibition of (Na(+)+K(+))-ATPase-mediated Ca2+ influx in cardiomyocytes. Biochem Biophys Res Commun. 2011;406:200-3 pubmed publisher
Landstrom A, Kellen C, Dixit S, van Oort R, Garbino A, Weisleder N, et al. Junctophilin-2 expression silencing causes cardiocyte hypertrophy and abnormal intracellular calcium-handling. Circ Heart Fail. 2011;4:214-23 pubmed publisher
Maier P, Marin I, Grampp T, Sommer A, Benke D. Sustained glutamate receptor activation down-regulates GABAB receptors by shifting the balance from recycling to lysosomal degradation. J Biol Chem. 2010;285:35606-14 pubmed publisher
Large R, Hollywood M, Sergeant G, Thornbury K, Bourke S, Levick J, et al. Ionic currents in intimal cultured synoviocytes from the rabbit. Am J Physiol Cell Physiol. 2010;299:C1180-94 pubmed publisher
Potier B, Turpin F, Sinet P, Rouaud E, Mothet J, Videau C, et al. Contribution of the d-Serine-Dependent Pathway to the Cellular Mechanisms Underlying Cognitive Aging. Front Aging Neurosci. 2010;2:1 pubmed publisher
Kyriazis G, Belal C, Madan M, Taylor D, Wang J, Wei Z, et al. Stress-induced switch in Numb isoforms enhances Notch-dependent expression of subtype-specific transient receptor potential channel. J Biol Chem. 2010;285:6811-25 pubmed publisher
Kato H, Watabe A, Manabe T. Non-Hebbian synaptic plasticity induced by repetitive postsynaptic action potentials. J Neurosci. 2009;29:11153-60 pubmed publisher
Ludwar B, Evans C, Jing J, Cropper E. Two distinct mechanisms mediate potentiating effects of depolarization on synaptic transmission. J Neurophysiol. 2009;102:1976-83 pubmed publisher
Soriano F, Martel M, Papadia S, Vaslin A, Baxter P, Rickman C, et al. Specific targeting of pro-death NMDA receptor signals with differing reliance on the NR2B PDZ ligand. J Neurosci. 2008;28:10696-710 pubmed publisher
Shin J, Kim Y, Linden D. Dendritic glutamate release produces autocrine activation of mGluR1 in cerebellar Purkinje cells. Proc Natl Acad Sci U S A. 2008;105:746-50 pubmed publisher
Ris L, Godaux E. Synapse specificity of long-term potentiation breaks down with aging. Learn Mem. 2007;14:185-9 pubmed
Villalba N, Stankevicius E, García Sacristán A, Simonsen U, Prieto D. Contribution of both Ca2+ entry and Ca2+ sensitization to the alpha1-adrenergic vasoconstriction of rat penile small arteries. Am J Physiol Heart Circ Physiol. 2007;292:H1157-69 pubmed
Wieland H, Hechtel N, Faigle M, Neumeister B. Efficient intracellular multiplication of Legionella pneumophila in human monocytes requires functional host cell L-type calcium channels. FEMS Immunol Med Microbiol. 2006;47:296-301 pubmed
Thiagarajan T, Lindskog M, Tsien R. Adaptation to synaptic inactivity in hippocampal neurons. Neuron. 2005;47:725-37 pubmed
Fujino T, Lee W, Nedivi E. Regulation of cpg15 by signaling pathways that mediate synaptic plasticity. Mol Cell Neurosci. 2003;24:538-54 pubmed
Hirasawa M, Pittman Q. Nifedipine facilitates neurotransmitter release independently of calcium channels. Proc Natl Acad Sci U S A. 2003;100:6139-44 pubmed
product information
master code :
1075
SKU :
1075/100
product name :
Nifedipine
unit size :
100 mg
description :
CaV1.x blocker
target :
Cav1.x Channel Blockers
category :
Small Molecules
purity :
98%
observed molecular weight :
346.34
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Nifedipine is a L-type calcium channel blocker.
top caption :
CaV1.x blocker
extended description :
CaV1.x blocker
chemical name text :
1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester
formula :
C17H18N2O6
formula text :
C17H18N2O6
cas num :
21829-25-4
USD :
113 USD
product details :
CaV1.x blocker
storage :
Desiccate at +4░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK