(RS)-APICA | Tocris Bioscience 1073 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

(RS)-APICA

catalog :

1073

quantity :

10 mg (also 50 mg)

price :

168 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Scholler P, Moreno Delgado D, Lecat Guillet N, Doumazane E, Monnier C, Charrier Savournin F, et al. HTS-compatible FRET-based conformational sensors clarify membrane receptor activation. Nat Chem Biol. 2017;13:372-380 pubmed publisher
Jiang Q, Yan Z, Feng J. Activation of group III metabotropic glutamate receptors attenuates rotenone toxicity on dopaminergic neurons through a microtubule-dependent mechanism. J Neurosci. 2006;26:4318-28 pubmed

product information

brand :

Tocris

master code :

1073

SKU :

1073/10

product name :

(RS)-APICA

description :

Selective group II mGlu antagonist

target :

Group II mGluR Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

observed molecular weight :

257.18

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Rigidified analog of MPPG (Cat. No. 0853); selective group II metabotropic glutamate receptor antagonist (IC50 = 30 u M) with no significant effect on group I and III mGlu receptors at concentrations up to 1 mM. Increases extracellular glutamate concentrations and possesses unusual inverse agonist-like action.

catalog number base :

1073

product keywords :

Selective group II antagonists mGlur Group Receptors mGlu2 mGlu3 mGluR2 mGluR3 Glutamate Metabotropic Glutamate (Metabotropic) Group II Receptors 1073,

extended description :

Selective group II mGlu antagonist

chemical name text :

(RS)-1-Amino-5-phosphonoindan-1-carboxylic acid

formula :

C 10 H 12 NO 5 P

formula text :

C10H12NO5P

cas num :

170847-18-4

2020 USD :

164

2021 USD :

168 USD

storage :

Desiccate at +4°C

more info or order :

Tocris Bioscience product webpage