product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
1068/500U
catalog :
1068/500U
quantity :
500 ug
price :
164 USD
more info or order :
citations: 9
Reference
Fergani C, Leon S, Padilla S, Verstegen A, Palmiter R, Navarro V. NKB signaling in the posterodorsal medial amygdala stimulates gonadotropin release in a kisspeptin-independent manner in female mice. elife. 2018;7: pubmed publisher
Zelikowsky M, Hui M, Karigo T, Choe A, Yang B, Blanco M, et al. The Neuropeptide Tac2 Controls a Distributed Brain State Induced by Chronic Social Isolation Stress. Cell. 2018;173:1265-1279.e19 pubmed publisher
León S, Barroso A, Vázquez M, García Galiano D, Manfredi Lozano M, Ruiz Pino F, et al. Direct Actions of Kisspeptins on GnRH Neurons Permit Attainment of Fertility but are Insufficient to Fully Preserve Gonadotropic Axis Activity. Sci Rep. 2016;6:19206 pubmed publisher
Navarro V, Bosch M, Leon S, Simavli S, True C, Pinilla L, et al. The integrated hypothalamic tachykinin-kisspeptin system as a central coordinator for reproduction. Endocrinology. 2015;156:627-37 pubmed publisher
Glidewell Kenney C, Shao P, Iyer A, Grove A, Meadows J, Mellon P. Neurokinin B causes acute GnRH secretion and repression of GnRH transcription in GT1-7 GnRH neurons. Mol Endocrinol. 2013;27:437-54 pubmed publisher
Grachev P, Li X, Lin Y, Hu M, Elsamani L, Paterson S, et al. GPR54-dependent stimulation of luteinizing hormone secretion by neurokinin B in prepubertal rats. PLoS ONE. 2012;7:e44344 pubmed publisher
Nestor C, Briscoe A, Davis S, Valent M, Goodman R, Hileman S. Evidence of a role for kisspeptin and neurokinin B in puberty of female sheep. Endocrinology. 2012;153:2756-65 pubmed publisher
Gallopin T, Geoffroy H, Rossier J, Lambolez B. Cortical sources of CRF, NKB, and CCK and their effects on pyramidal cells in the neocortex. Cereb Cortex. 2006;16:1440-52 pubmed
Howe H, Somponpun S, Sladek C. Role of neurokinin 3 receptors in supraoptic vasopressin and oxytocin neurons. J Neurosci. 2004;24:10103-10 pubmed
product information
master code :
1068
SKU :
1068/500U
product name :
Senktide
unit size :
500 ug
description :
Tachykinin NK3 agonist
target :
NK3 Receptor Agonists
category :
Peptides
purity :
95%
observed molecular weight :
841.97
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=peptides
details of functionality :
Senktide is a NK3 tachykinin receptor agonist. Causes direct excitation of dopamine neurons; enhances dopaminergic function. Induces locomotor activity.
top caption :
Tachykinin NK3 agonist
extended description :
Tachykinin NK3 agonist
formula :
C40H55N7O11S
formula text :
C40H55N7O11S
cas num :
106128-89-6
USD :
164 USD
product details :
Tachykinin NK3 agonist
storage :
Store at -20░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK