product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
1067/100
catalog :
1067/100
quantity :
100 mg
price :
164 USD
more info or order :
citations: 15
Reference
Raza S, Albrecht A, Caliskan G, Muller B, Demiray Y, Ludewig S, et al. HIPP neurons in the dentate gyrus mediate the cholinergic modulation of background context memory salience. Nat Commun. 2017;8:189 pubmed publisher
Parent M, Amarante L, Swanson K, Laubach M. Cholinergic and ghrelinergic receptors and KCNQ channels in the medial PFC regulate the expression of palatability. Front Behav Neurosci. 2015;9:284 pubmed publisher
Roberts Crowley M, Rittenhouse A. Characterization of ST14A Cells for Studying Modulation of Voltage-Gated Calcium Channels. PLoS ONE. 2015;10:e0132469 pubmed publisher
Shin J, Adrover M, Wess J, Alvarez V. Muscarinic regulation of dopamine and glutamate transmission in the nucleus accumbens. Proc Natl Acad Sci U S A. 2015;112:8124-9 pubmed publisher
Abiraman K, Pol S, O Bara M, Chen G, Khaku Z, Wang J, et al. Anti-muscarinic adjunct therapy accelerates functional human oligodendrocyte repair. J Neurosci. 2015;35:3676-88 pubmed publisher
Wilke B, Lindner M, Greifenberg L, Albus A, Kronimus Y, Bünemann M, et al. Diacylglycerol mediates regulation of TASK potassium channels by Gq-coupled receptors. Nat Commun. 2014;5:5540 pubmed publisher
Saxena S, Roselli F, Singh K, Leptien K, Julien J, Gros Louis F, et al. Neuroprotection through excitability and mTOR required in ALS motoneurons to delay disease and extend survival. Neuron. 2013;80:80-96 pubmed publisher
Deng H, Sun H, Fang Y. Label-free cell phenotypic assessment of the biased agonism and efficacy of agonists at the endogenous muscarinic M3 receptors. J Pharmacol Toxicol Methods. 2013;68:323-33 pubmed publisher
Daigle T, Caron M. Elimination of GRK2 from cholinergic neurons reduces behavioral sensitivity to muscarinic receptor activation. J Neurosci. 2012;32:11461-6 pubmed publisher
Won Y, Ono F, Ikeda S. Characterization of Na+ and Ca2+ channels in zebrafish dorsal root ganglion neurons. PLoS ONE. 2012;7:e42602 pubmed publisher
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher
Buchanan K, Petrovic M, Chamberlain S, Marrion N, Mellor J. Facilitation of long-term potentiation by muscarinic M(1) receptors is mediated by inhibition of SK channels. Neuron. 2010;68:948-63 pubmed publisher
Won Y, Ono F, Ikeda S. Identification and modulation of voltage-gated Ca2+ currents in zebrafish Rohon-Beard neurons. J Neurophysiol. 2011;105:442-53 pubmed publisher
Filippov A, Simon J, Barnard E, Brown D. The scaffold protein NHERF2 determines the coupling of P2Y1 nucleotide and mGluR5 glutamate receptor to different ion channels in neurons. J Neurosci. 2010;30:11068-72 pubmed publisher
Narushima M, Uchigashima M, Fukaya M, Matsui M, Manabe T, Hashimoto K, et al. Tonic enhancement of endocannabinoid-mediated retrograde suppression of inhibition by cholinergic interneuron activity in the striatum. J Neurosci. 2007;27:496-506 pubmed
product information
master code :
1067
SKU :
1067/100
product name :
Oxotremorine M
unit size :
100 mg
description :
Muscarinic agonist
target :
Non-selective mAChR Agonists
category :
Small Molecules
purity :
98%
observed molecular weight :
322.19
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Oxotremorine M is a muscarinic receptor agonist. Also directly potentiates NMDA-mediated ion currents.
top caption :
Muscarinic agonist
extended description :
Muscarinic agonist
chemical name text :
N,N,N-Trimethyl-4-(2-oxo-1-pyrolidinyl)-2-butyn-1-ammonium iodide
formula :
C11H19IN2O
formula text :
C11H19IN2O
cas num :
4/4/54
USD :
164 USD
product details :
Muscarinic agonist
storage :
Desiccate at -20░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK