product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
1064/10
catalog :
1064/10
quantity :
10 mg (also 50 mg)
price :
286 USD
more info or order :
citations: 9
Reference
Kapoor V, Provost A, Agarwal P, Murthy V. Activation of raphe nuclei triggers rapid and distinct effects on parallel olfactory bulb output channels. Nat Neurosci. 2016;19:271-82 pubmed publisher
Williams A, Ingram W, LeVine S, Resnik J, Kamel C, Lish J, et al. Reduced levels of serotonin 2A receptors underlie resistance of Egr3-deficient mice to locomotor suppression by clozapine. Neuropsychopharmacology. 2012;37:2285-98 pubmed publisher
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher
Murray K, Stephens M, Rank M, D Amico J, Gorassini M, Bennett D. Polysynaptic excitatory postsynaptic potentials that trigger spasms after spinal cord injury in rats are inhibited by 5-HT1B and 5-HT1F receptors. J Neurophysiol. 2011;106:925-43 pubmed publisher
Moreno J, Kurita M, Holloway T, Lopez J, Cadagan R, Martinez Sobrido L, et al. Maternal influenza viral infection causes schizophrenia-like alterations of 5-HT?A and mGlu? receptors in the adult offspring. J Neurosci. 2011;31:1863-72 pubmed publisher
Murray K, Nakae A, Stephens M, Rank M, D Amico J, Harvey P, et al. Recovery of motoneuron and locomotor function after spinal cord injury depends on constitutive activity in 5-HT2C receptors. Nat Med. 2010;16:694-700 pubmed publisher
Huang Y, Dando R, Roper S. Autocrine and paracrine roles for ATP and serotonin in mouse taste buds. J Neurosci. 2009;29:13909-18 pubmed publisher
Dacks A, Green D, Root C, Nighorn A, Wang J. Serotonin modulates olfactory processing in the antennal lobe of Drosophila. J Neurogenet. 2009;23:366-77 pubmed publisher
Gonzalez Maeso J, Weisstaub N, Zhou M, Chan P, Ivic L, Ang R, et al. Hallucinogens recruit specific cortical 5-HT(2A) receptor-mediated signaling pathways to affect behavior. Neuron. 2007;53:439-52 pubmed
image
image 1 :
Tocris Bioscience 1064/10 image 1
Cat.No. 1064 - Methysergide maleate C21H27N3O2.C4H4O4 CAS No. 129-49-7
product information
master code :
1064
SKU :
1064/10
product name :
Methysergide maleate
unit size :
10 mg (also 50 mg)
description :
5-HT1/5-HT2 antagonist
target :
Non-selective 5-HT Receptor Antagonists
category :
Small Molecules
purity :
99%
observed molecular weight :
469.54
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Methysergide maleate is a mixed 5-HT1/5-HT2 receptor antagonist.
top caption :
5-HT1/5-HT2 antagonist
extended description :
5-HT1/5-HT2 antagonist
chemical name text :
[8 (S)]-9,10-Didehydro-N-[1-(hydroxymethyl)propyl]-1,6-dimethylergoline-8-carboxamide maleate
formula :
C21H27N3O2.C4H4O4
formula text :
C21H27N3O2.C4H4O4
cas num :
129-49-7
USD :
286 USD
product details :
5-HT1/5-HT2 antagonist
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK