product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
1061/10
catalog :
1061/10
quantity :
10 mg (also 50 mg)
price :
167 USD
more info or order :
citations: 46
Reference
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Beas B, Wright B, Skirzewski M, Leng Y, Hyun J, Koita O, et al. The locus coeruleus drives disinhibition in the midline thalamus via a dopaminergic mechanism. Nat Neurosci. 2018;21:963-973 pubmed publisher
Jain S, Panyutin A, Liu N, Xiao C, Pinol R, Pundir P, et al. Melanotan II causes hypothermia in mice by activation of mast cells and stimulation of histamine 1 receptors. Am J Physiol Endocrinol Metab. 2018;315:E357-E366 pubmed publisher
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Leng Z, Lin S, Wu Z, Guo Y, Cai L, Shang H, et al. Activation of DRD5 (dopamine receptor D5) inhibits tumor growth by autophagic cell death. Autophagy. 2017;13:1404-1419 pubmed publisher
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Picton L, Sillar K. Mechanisms underlying the endogenous dopaminergic inhibition of spinal locomotor circuit function in Xenopus tadpoles. Sci Rep. 2016;6:35749 pubmed publisher
Borgs L, Peyre E, Alix P, Hanon K, Grobarczyk B, Godin J, et al. Dopaminergic neurons differentiating from LRRK2 G2019S induced pluripotent stem cells show early neuritic branching defects. Sci Rep. 2016;6:33377 pubmed publisher
Hedlund E, Belnoue L, Theofilopoulos S, Salto C, Bye C, Parish C, et al. Dopamine Receptor Antagonists Enhance Proliferation and Neurogenesis of Midbrain Lmx1a-expressing Progenitors. Sci Rep. 2016;6:26448 pubmed publisher
Dwyer J, Leslie F. Adolescent Maturation of Dopamine D1 and D2 Receptor Function and Interactions in Rodents. PLoS ONE. 2016;11:e0146966 pubmed publisher
Wang J, Cao Y, Li Q, Yang Y, Jin M, Chen D, et al. A pivotal role of FOS-mediated BECN1/Beclin 1 upregulation in dopamine D2 and D3 receptor agonist-induced autophagy activation. Autophagy. 2015;11:2057-2073 pubmed publisher
Xing L, McDonald H, Da Fonte D, Gutierrez Villagomez J, Trudeau V. Dopamine D1 receptor activation regulates the expression of the estrogen synthesis gene aromatase B in radial glial cells. Front Neurosci. 2015;9:310 pubmed publisher
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product information
master code :
1061
SKU :
1061/10
product name :
(-)-Quinpirole hydrochloride
unit size :
10 mg (also 50 mg)
description :
Selective D2-like agonist
target :
Non-selective Dopamine Receptor Agonists
category :
Small Molecules
purity :
98%
observed molecular weight :
255.79
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
(-)-Quinpirole hydrochloride is a selective dopamine D2 receptor agonist (Ki values are 4.8, ~24, ~30 and 1900 nM at D2, D3, D4 and D1 receptors respectively).
top caption :
Selective D2-like agonist
extended description :
Selective D2-like agonist
chemical name text :
(4aR-trans)-4,4a,5,6,7,8,8a,9-Octahydro-5-propyl-1H-pyrazolo[3,4-g]quinoline hydrochloride
formula :
C13H21N3.HCl
formula text :
C13H21N3.HCl
cas num :
85798-08-9
USD :
167 USD
product details :
Selective D2-like agonist
storage :
Desiccate at -20░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK